اسکوتوفوبین (SCOTOPHOBIN)
نویسنده
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Synthetic scotophobin: analysis of behavioral effects on mice.
MALIN, D. H. Synthetic scotophobin: analysis of behavioral effects on mice. PHARMAC. BIoCHEM. BEHAV. 2(2) 147-153, 1974. Scotophobin is a peptide previously identified [ 141 as the behaviorally active factor in brain extract of rats trained in passive dark avoidance. Mice injected intraperitoneally with a synthetic version of scotophobin or placebo were tested without reinforcement in a box wit...
متن کاملThe effect of synthetic scotophobin on motor activity in mice.
The motor activity of mice treated by scotophobin (1, 2, 4, 6 micrograms) was tested in a photoresistor actometer 24, 48 and 72 h after injection. Scotophobin in doses of 4 and 6 micrograms per mouse increased significantly the motor activity as compared with controls injected with saline only. This result suggests that shortening of dark box time, found by some authors after injection of scoto...
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This study attempted to elucidate the controversy surrounding the experiments of Ungar examining the effects of scotophobin on dark preference in mice. The behavior of 45 noninjected mice in the type of maze described by Ungar was examined. Seven subsequent tests were conducted for dark box time (DBT) and motor activity. In general, the results indicated that DBT in all subpopulations of mice s...
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whereas positive values denote faster learning in SP fish (SP> C) (14). A differential effect of scotophobin may be seen on light-avoidance and darkavoidance learning (15). This differential inhibition or facilitation varies over the period of conditioning. When averaged across days (Fig. 2), the effect may also be seen. It is unlikely -that the effect of scotophobin should be equally strong at...
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عنوان ژورنال
دوره 30 شماره None
صفحات 71- 72
تاریخ انتشار 1972-05
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