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بررسی تأثیر مداخلات روانپزشکی در بروز حاملگی زوجین نابارور

نویسندگان

  • باقری, مریم گروه زنان، مرکز تحقیقات بهداشت باروری دانشگاه علوم پزشکی تهران
  • تهرانی‌نژاد, انسیه گروه زنان، مرکز تحقیقات بهداشت باروری دانشگاه علوم پزشکی تهران
  • رحیمی فروشانی, عباس گروه اپیدمیولوژی، دانشکده بهداشت دانشگاه علوم پزشکی تهران
  • سهراب‌وند, فرناز گروه زنان، مرکز تحقیقات بهداشت باروری دانشگاه علوم پزشکی تهران
  • شریعت, مامک گروه نوزادان دانشگاه علوم پزشکی تهران
  • نوربالا, احمدعلی گروه روانپزشکی و مرکز تحقیقات روانپزشکی دانشگاه علوم پزشکی تهران
  • رشیدی, بتول گروه زنان، مرکز تحقیقات بهداشت باروری دانشگاه علوم پزشکی تهران
  • عابدی‌نیا, نسرین گروه روانپزشکی و مرکز تحقیقات روانپزشکی دانشگاه علوم پزشکی تهران
  • ملک افضلی, حسین گروه اپیدمیولوژی، دانشکده بهداشت دانشگاه علوم پزشکی تهران

چکیده

Background: Considering the psycho-social model of diseases, the aim of this study was to evaluate the effect of psychiatric intervention on the pregnancy rate of infertile couples.Methods: In a randomized clinical trial, 638 infertile patients referred to a university infertility clinic were evaluated. Among them, 140 couples with different levels of depression in at least one of the spouses were included in this substudy. These couples were divided randomly into two groups. The patients in the case group received 6-8 sessions of psychotherapy before starting infertility treatment and were given fluoxetine 20-60 mg per day during the same period. The control group did not receive any intervention. Three questionnaires including the Beck Depression Inventory (BDI), Holmes-Rahe stress scale and a socio-demographic questionnaire were applied for all patients. The clinical pregnancy rates of the two groups, based on sonographic detection of the gestational sac six weeks after LMP, were compared. The data were analyzed by paired-T test, T-test, χ2 and the logistic regression method. Results: The pregnancy rate was 47.1% in the case group and 7.1% in the control group. The pregnancy rate was significantly related to the duration and cause of infertility and the level of stress in both groups (p< 0.001). The pregnancy rate was shown to be higher in couples in which the male has a secondary level of education (p< 0.001).Conclusions: Psychiatric interventions greatly improve pregnancy rates, and it is therefore crucial to mandate psychiatric counseling in all fertility centers in order to diagnose and treat infertile patients with psychiatric disorders and help couples deal with stress.

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