بررسی مقایسه ای اثر لیدوکائین ، فنتانیل و پلاسبو بر تغییرات همودینامیک به دنبال ساکشن لوله داخل تراشه در بیماران بستری در ICU

          Suction of endotracheal tube in ICU can cause hemodynamic    changes. We compare the effect of lidocaine , fentanyl and placebo on    reducing hemodynamic changes following suction in ICU patient.           Patients were divided into three groups , each containing twenty two    patients: A- Lidocaine group receiving 1.5 mg/kg lidocaine intravenously    two minutes before suction , B- Fentanyl group receiving 3 mg/kg fentanyl    two minutes before suction , C- Placebo receiving distilled water . The    total volume of the three substances  was raised to 5 cc. Injecting the drugs    and suctioning in a standard technique , we recorded mean arterial    pressure , pulse rate , arterial oxygen saturation three times : immediately ,    after three and six minute’s . The recorded information was analyzed.           Based on the results , the injection of Lidocaine before suctioning    prevented the hemodynamic changes and hypoxemia , which happened    after endotracheal suction. Fentanyl caused hypotension and bradycardia ,    rejecting the previous reported research. Suctioning in the placebos    resulted in hypotension , bradycardia and hypoxemia.           We can use intravenous lidocaine before endotracheal suction to    prevent hemodynamic changes in ICU patients.