خواص آنتی‌اکسیدانی عصاره هیدروالکلی و اسانس روغنی گیاه درمنه (emisa persicaArt): مقاله کوتاه

Background and Aim: Consumption of plant derived antioxidant compounds contributes to reducing risks of certain chronic and degenerative diseases. The present study aimed at comparing various antioxidative activities hydroalcholic of flaver extract (DKME) and essential oil of Artemisa persica in Lorestan province in 2012. Materials and Methods: The present experimental study was carried out in Lorestan province in 2012 . After supplying hydroalcholic extract and essential oil of Artemisa persica , radical scavenging activity of the samples was assessed by using diphenylpicrylhydrazyl (DPPH). Total antioxidant capacity of the samples was assessed through phosphomolybdat method. The amount of total phenol and flavonoid samples was assessed by means of Folin-Ciocalteu and Zhishen methods. The obtained data was analysed using Kruskal-Wallis test and SPSS software (V: 13) at the significant level (P<0.05). Results: It was found that total antioxidant capacity of hydroalcholic extract and essential oil of Artemisa persica was 25.123±5.18 and 1.05±0.55 nmol of ascorbic acid equivalent/g extract, respectively.That of essential oil and phenol content was 326.68±10.07 and 131.14±3mg of gallic acid equivalent (GAE)/g extract or essential oil, respectively .Flavonoid content of quercetin equivalents/g extract and essential oil was 6.3±0.94 and 1.4±0.65 mg , in the order mentioned. In the DPPH scavenging assay, the IC50 (the concentration required to scavenge 50% of radicals) values of hydroalcholic extract of Artemisa Persica leaves, essential oil and Butylated hydroxytoluene (BHT) as reference was 165.73±4, 16470.67±34, and 3.88±1μg/ml, respectively. Conclusion: The current study showed that Artemisa persica extract is an easily accessible source of natural antioxidants which can be suitable to be included in foods and pharmaceutical applications.