An Investigation of the Relationship between Serum Vitamin E Status and Coronary Risk Factors in Dyslipidaemic Patients

نویسندگان

  • Amir Hossein Sahebkar School of Pharmacy, MUMS, Mashad, Iran, Postal Code: 91775-1365
  • Bryan Starkey Centre for Clinical Science & Measurement, University of Surrey, Stag Hill, Guildford, Surrey, GU2 7XH, United Kingdom
  • Callum Livingstone Centre for Clinical Science & Measurement, University of Surrey, Stag Hill, Guildford, Surrey, GU2 7XH, United Kingdom
  • David Lamb Centre for Clinical Science & Measurement, University of Surrey, Stag Hill, Guildford, Surrey, GU2 7XH, United Kingdom
  • Gordon Ferns Centre for Clinical Science & Measurement, University of Surrey, Stag Hill, Guildford, Surrey, GU2 7XH, United Kingdom
  • Majid Ghayour-Mobarhan Cardiovascular Research Center, Avicenna Research Institute, Mashhad University of Medical Sciences (MUMS), Mashhad, Iran|Department of Nutrition and Biochemistry, Faculty of Medicine, MUMS, Mashhad, Iran.
  • Tim Wang Centre for Clinical Science & Measurement, University of Surrey, Stag Hill, Guildford, Surrey, GU2 7XH, United Kingdom
چکیده

Objective Vitamin E is a major lipid-soluble antioxidant. It has been demonstrated that vitamin E supplementation has a beneficial effect against coronary heart disease (CHD). This study to investigate the effects of coronary risk factors on serum vitamin E status in patients with dyslipidaemia. Materials and Methods This tertiary care hospital; case - control study was comprised 237 dyslipidaemic patients and 135 healthy individuals recruited from university and hospital employees. Serum vitamin E concentration was measured using high performance liquid chromatography (HPLC). Results Compared to the healthy individuals, the dyslipidaemic patients had higher serum vitamin E (p0.05). Serum vitamin E did not differ between subcategories of dyslipidaemic patients with and without coronary risk factors (p>0.05), but Serum vitamin E / total cholesterol ratio was higher in patients with established coronary heart disease (p

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an investigation of the relationship between serum vitamin e status and coronary risk factors in dyslipidaemic patients

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عنوان ژورنال:

دوره 10  شماره 4

صفحات  206- 215

تاریخ انتشار 2008-10-01

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