Commentary: Comparison of activated charcoal and sodium polystyrene sulfonate resin efficiency on reduction of amitriptyline oral absorption in rat as treatments for overdose and toxicities

نویسندگان

  • Morgan Riggan Division of Medical Toxicology, Ronald O Perelman Department of Emergency Medicine, New York University School of Medicine
  • Robert Hoffman Division of Medical Toxicology, Ronald O Perelman Department of Emergency Medicine, New York University School of Medicine
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Comparison of activated charcoal and sodium polystyrene sulfonate resin efficiency on reduction of amitriptyline oral absorption in rat as treatments for overdose and toxicities

Objective(s): Comparative in vivo studies were carried out to determine the adsorption characteristics of amitriptyline (AMT) on activated charcoal (AC) and sodium polystyrene sulfonate (SPS). AC has been long used as gastric decontamination agent for tricyclic antidepressants and SPS has showed to be highly effective on in-vitro drugs adsorption. Materials and Methods: Sprague-Dawley male rats...

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comparison of activated charcoal and sodium polystyrene sulfonate resin efficiency on reduction of amitriptyline oral absorption in rat as treatments for overdose and toxicities

objective(s): comparative in vivo studies were carried out to determine the adsorption characteristics of amitriptyline (amt) on activated charcoal (ac) and sodium polystyrene sulfonate (sps). ac has been long used as gastric decontamination agent for tricyclic antidepressants and sps has showed to be highly effective on in-vitro drugs adsorption. materials and methods: sprague-dawley male rats...

متن کامل

Comparison of activated charcoal and sodium polystyrene sulfonate resin efficiency on reduction of amitriptyline oral absorption in rat as treatments for overdose and toxicities

OBJECTIVES Comparative in vivo studies were carried out to determine the adsorption characteristics of amitriptyline (AMT) on activated charcoal (AC) and sodium polystyrene sulfonate (SPS). AC has been long used as gastric decontamination agent for tricyclic antidepressants and SPS has showed to be highly effective on in-vitro drugs adsorption. MATERIALS AND METHODS Sprague-Dawley male rats w...

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عنوان ژورنال

دوره 20  شماره 5

صفحات  457- 457

تاریخ انتشار 2017-05-01

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