Diagnosis of viral myocarditis in children by multiplex real-time PCR in Vali-Asr Hospital, Birjand, eastern Iran
Background and Objective: Viral myocarditis (VMC) is one of the common heart diseases to endanger human health in different age groups, especially children. The aim of this study was to diagnose VMC in children with clinical suspicion of myocarditis (MCI) using multiplex real-time PCR in Birjand Vali-Asr Hospital. Methods: This cross-sectional study was conducted on 19 patients with clinical suspicion of MCI, who had evidence of infections in the recent weeks. Routine electrocardiogram and dynamic electrocardiogram (ECG) examinations, auxiliary laboratory testing and echocardiographic evaluation were performed. Multiplex real-time PCR was used for detection of viral agents in blood or pericardial fluid samples. Findings: The results indicated that 4 out of 19 (21.05%) MCI patients were virus-positive. The spectrum of viral agents included human herpesvirus 6, 7 (HHV), parvovirus B-19 (PVB19), Epstein–Barr virus (EBV), varicella zoster virus (VZV) and adenoviruses. A co-infection of HHV-6, 7 and PVB19 was found in one patient. The ECG findings such as sinus tachycardia with ST-T changes, premature ventricular contraction and complete heart block were observed in VMC patients. The predominant echocardiographic features in VMC patients were low ejection fraction, mitral regurgitation and severe pericardial effusion with hypotension. Aspartate aminotransferase (AST) and lactic dehydrogenase (LDH) had abnormal increase in some patients. Conclusion: Our findings highlight the importance of identification of VMC in children with clinical suspicion of MCI. The present study emphasizes the importance of PCR-based assays for detection of viral agents in MCI patients with symptoms of virus infection.
Hearing loss and eye refractive disorders in patients admitted to Vali-e- Asr Hospital in Birjand, Iran, 2015
Introduction: There is insufficient information about the correlation between hearing and visual impairments. Its importance arises when trainers should care about medical issues of their clients. Refractive errors of the eye are one of the main causes of visual loss in the society. The purpose of this study was to evaluate the relationship between refractive errors in the eye (by the type of r...متن کامل
Evaluation of relationship between presbyopia and presbycusis in Vali-e-Asr Hospital in Birjand, Iran, during 2014-2015
Introduction: Presbyopia and presbycusis are common disorders in aging people leading to various negative consequences, such as social problems, cognitive disorders, depression, and imbalance. The combination of vision and hearing loss has been correlated with various adverse outcomes. Regarding the adverse effect of presbyopia and presbycusis on communication skills and quality of life in indi...متن کامل
The association between oxygen saturation and cataract disease and related factors in Birjand Vali-asr Hospital
Introduction: Any opacity of lens is defined as cataract. This leads to reduced vision that is the most common cause of blindness in the world in among the elderly. There is no non-surgical treatment for cataract patients; thereby, patients have to spend a lot of money especially those residing in the undeveloped countries. It is thus necessary to be informed of predisposing factors in order to...متن کامل
Dear Editor, Nasal polyp is a common chronic inflammatory disease of the sinonasal mucosa that is histologically characterized by infiltration of eosinophils and large quantities of extracellular edema. It causes considerable morbidity such as nasal obstruction, rhinorrhea and sleep disorders. Pathogenesis of nasal polyps is still debatable. Helicobacter pylori may play a role in the pathogenes...متن کامل
A study of the Complications of Bipolar Electrocautery Tonsillectomy in Patients Admitted to Vali-e-Asr Hospital of Birjand
Introduction: Tonsillectomy is one of the most common surgeries all over the world and is performed by various methods. This study aimed to investigate the complications of bipolar electrocautery method of tonsillectomy. Methods: This cross-sectional study was performed on 234 patients, 114 female and 120 male individuals. The mean age of the patients was 12.2±8.3 (min=3 and max=58.2) years....متن کامل
BACKGROUND Asphyxia is a medical condition in which placental or pulmonary gas exchange is impaired or they cease all together, typically producing a combination of progressive hypoxemia and hypercapnea. OBJECTIVE In addition to regional differences in its etiology; it is important to know its risk factors. MATERIALS AND METHODS This is a case-control study, all neonates born from May 2002 ...متن کامل
دوره 7 شماره 1
صفحات 458- 464
تاریخ انتشار 2021-02
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.