Evaluation of Antibiotic Resistance to Fluoroquinolones and Third Generation Cephalosporines in Iranian Clinical Isolates of Salmonella spp.

نویسندگان

  • Alireza Azizi Saraji Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran
  • AmadReza Salehi chaleshtori Young Researchers Club, Shahrekord Branch, Islamic Azad University, PO BOX 166
  • Bahareh Rajaei Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran
  • Mariam Amin Eshghabadi Department of Parasit ology, Pasteur Institute of Iran, Tehran, Iran
  • Mohammad Doroudian Young Researchers and Elite club, Central Tehran Branch, Islamic Azad University, Tehran, Iran
  • Mohammad Reza Aghasadeghi Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran.
  • Nahid Sepehri Rad Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
  • Roqiah Gholizadeh Doran Mahaleh Department of Medical Sciences, Isl amic Azad University, Zahedan, Iran
  • Seyed Davar Siadat Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran.
  • Somieh Khanjani Jafroodi Department of Parasit ology, Pasteur Institute of Iran, Tehran, Iran
چکیده مقاله:

Salmonella enterica serotypes are one of the most important food borne pathogens and significant public health concerns around the world in humans and other animal species. A total of eighty three epidemiologically unrelated clinical isolates of Salmonella enterica serovars were subjected to antimicrobial susceptibility testing. Eleven isolates (13.1%) which were resistant to at least 4 groups of antimicrobial agents considered as multidrug resistant (MDR) Salmonella serovars. Emergence of MDR Salmonella serovars demonstrates that antimicrobial selection pressure is widespread in our clinical settings. According to the results of antimicrobial susceptibility testing, Salmonella clinical isolates are more susceptible to fluoroquinolones and third generation cephalosporins and these drugs may be used as drugs of choice to treat Salmonella infections.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

evaluation of antibiotic resistance to fluoroquinolones and third generation cephalosporines in iranian clinical isolates of salmonella spp.

salmonella enterica serotypes are one of the most important food borne pathogens and significant public health concerns around the world in humans and other animal species. a total of eighty three epidemiologically unrelated clinical isolates of salmonella enterica serovars were subjected to antimicrobial susceptibility testing. eleven isolates (13.1%) which were resistant to at least 4 groups ...

متن کامل

Evaluation of Resistance to Fluoroquinolones and Its Relationship whit parC Gene Mutation in Klebsiella pneumoniae Clinical Isolates

Background & Objective: Klebsiella pneumoniae has received attention due to a wide range of diseases and antibiotic resistance.The resistance to fluoroquinolones in gram-negative bacteria is often due to chromosomal mutations in the gyr and par genes. This research aimed at investigating the pattern of fluoroquinolone resistance and its relation with a mutation in the parC gene among clinical i...

متن کامل

Contribution of different mechanisms to the resistance to fluoroquinolones in clinical isolates of Salmonella enterica.

OBJECTIVES To study the potential factors include gene mutation, efflux pump and alteration of permeability associated with quinolone-resistance of Salmonella enterica strains isolated from patients with acute gastroenteritis and to evaluate the degree of synergistic activity of efflux pump inhibitors when combined with ciprofloxacin against resistant isolates. METHODS Antimicrobial resistanc...

متن کامل

Evaluation of Antibiotic Resistance Patterns of Clinical Klebsiella pneumoniae Isolates from Educational Hospitals in Zahedan, Iran

ABSTRACT Background and Objectives: The resistance of gram-negative bacteria to antibiotics has become a serious problem, which imposes a significant increase in treatment costs. Klebsiella pneumoniae is an important nosocomial pathogen from the Enterobacteriaceae family. The aim of this study was to investigate the frequency and pattern of antibiotic resistance in K. pneumoniae strains isolat...

متن کامل

an investigation into iranian teachers consistency and bias in evaluation of students writings

while performance-based language assessment has led to an increased authenticity and content validity in the practice of writing assessment, the reliability of ratings has become a major issue. research findings have shown different reactions by native english speaker (nes) and non-native english speaker (nns) teachers to students’ writings. the focus of this study is on investigating whether i...

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 2  شماره 2

صفحات  194- 198

تاریخ انتشار 2012-11-01

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023