P7: Valproic Acid Mediated Neuroprotection and Neurogenesis after Acute Spinal Cord Injury

نویسندگان

  • Abdolahi, Sara a. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran b. Department of Biotechnology, School of Veterinary Science, Shiraz University, Shiraz, Iran
  • Borhani-Haghighi, Maryam a. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran b. Department of Anatomy, Tehran University of Medical Science, Tehran, Iran
  • Hosseini Ravandi, Hassan a.Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran
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p7: valproic acid mediated neuroprotection and neurogenesis after acute spinal cord injury

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The Neuroprotective Effect of Treatment of Valproic Acid in Acute Spinal Cord Injury

OBJECTIVE Valproic acid (VPA), as known as histone deacetylase inhibitor, has neuroprotective effects. This study investigated the histological changes and functional recovery from spinal cord injury (SCI) associated with VPA treatment in a rat model. METHODS Locomotor function was assessed according to the Basso-Beattie-Bresnahan scale for 2 weeks in rats after receiving twice daily intraper...

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عنوان ژورنال

دوره 3  شماره 4

صفحات  34- 34

تاریخ انتشار 2015-12

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