P75: Toward Treatment of Post-Traumatic Spinal Cord Injury: Differentiation of Oligodendrocytes from Bone Marrow Stem Cells

نویسنده

Alizadeh, Leila Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran.

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P71: Toward Treatment of Post-Traumatic Spinal Cord Injury: Differentiation of Oligodendrocytes from Adipose Stem Cells

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p75: toward treatment of post-traumatic spinal cord injury: differentiation of oligodendrocytes from bone marrow stem cells

traumatic central nervous system injuries lead to a severe and permanent neurological deficit. oligodendrocytes (olcs) are vulnerable to damage in a variety of neurologic diseases. although no effective therapeutic option is currently available, recent other studies have shown that cell therapeutic strategies hold promise to enhance functional recovery after injury. the aim of this study is to ...

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Impacts of Bone Marrow Stem Cells on Caspase-3 Levels after Spinal Cord Injury in Mice

Spinal cord injury (SCI) is a drastic disability that leads to spinal cord impairment. This study sought to determine the effects of bone marrow stem cells (BMSCs) on caspase-3 levels after acute SCI in mice. Forty-two mice were randomly divided into 3 groups: control (2 subcategories), subjected to no intervention; sham (3 subcategories), subjected to acute SCI; and experimental (2 subcategori...

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Improvement of Spinal Cord Injury in Rat Model via Transplantation of Neural Stem Cells Derived From Bone Marrow

Abstract Background & Aims: Cell therapy is among the novel therapeutic methods effective in the treatment of spinal cord injuries. The aim of the present study was using neural stem cells (NSCs) in treating contusion spinal cord injury in rat model. Methods: Bone marrow stromal cells (BMSCs) were isolated from adult rats...

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Transplanting P75-Suppressed Bone Marrow Stromal Cells Promotes Functional Behavior in a Rat Model of Spinal Cord Injury

Background: Bone marrow stromal cells (BMSC) have been successfully employed for movement deficit recovery in spinal cord injury (SCI) rat models. One of the unsettled problems in cell transplantation is the relative high proportion of cell death, specifically after neural differentiation. According to our previous studies, p75 receptor, known as the death receptor, is only expressed in BMSC in...

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