Review of Natural History, Benefits and Risk Factors Pediatric Liver Transplantation

نویسندگان

  • Manoochehr Karjoo Professor, Pediatric Gastroenterology, Hepatology and Nutrition, Golisano Children's Hospital, Upstate Medical University, 725 Irving Avenue, Suite 504, Syracuse NY 13210.
  • Maryam Banikazemi Professor, Pediatric Hematology, Columbia University, 403 E 34th St, New York, NY 10016, United States.
  • Masumeh Saeidi Students Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Mohammad Ali Kiani Associate Professor of Pediatric Gastroenterology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده

Liver or hepatic transplantation (LT) is the replacement of a diseased liver with part or whole healthy liver from another person (allograft). Human liver transplants were first performed by Thomas Starzl in the United States and Roy Calne in Cambridge, England in 1963 and 1967, respectively. Liver transplantation is a viable treatment option for end-stage liver disease and acute liver failure. Pediatric patients account for about 12.5% of liver transplant recipients. The most commonly used technique is orthotopic transplantation, in which the native liver is removed and replaced by the donor organ in the same anatomic location as the original liver. Cirrhosis, or liver injury, is a common reason why adults need liver transplants and children with bile duct disease issues are often the candidates. Survival statistics depend greatly on the age of donor, age of recipient, skill of the transplant center, compliance of the recipient, whether the organ came from a living or cadaveric donor and overall health of the recipient. Survival rates improve almost yearly, due to improved techniques and medications.

برای دانلود باید عضویت طلایی داشته باشید

برای دسترسی به متن کامل این مقاله و 23 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

review of natural history, benefits and risk factors pediatric liver transplantation

liver or hepatic transplantation (lt) is the replacement of a diseased liver with part or whole healthy liver from another person (allograft). human liver transplants were first performed by thomas starzl in the united states and roy calne in cambridge, england in 1963 and 1967, respectively. liver transplantation is a viable treatment option for end-stage liver disease and acute liver failure....

متن کامل

Short and Long Term Complications after Pediatric Liver Transplantation: A Review and Literature

Background: Pediatric liver transplant is a complex surgical procedure. Pediatric liver transplantation has evolved over the last two decades into an effective and widely accepted therapy for infants and children. The aim of our report is to review the current state of knowledge and explore the incidence of complications, the involved pathogens among liver recipients to determine the effective ...

متن کامل

Natural history of hepatitis B and outcomes after liver transplantation.

HBV infection is the single most common cause of cirrhosis globally although the prevalence rate is influenced by geographic region. The natural course of HBV infection and the clinical outcome is dependent on the interplay between host, virus, and environmental factors. Understanding the natural history of HBV infection is important in determining treatment strategies. OLT is the ultimate cure...

متن کامل

Cardiovascular Risk Factors and Liver Transplantation

In the last decades, the survival of liver transplanted patients and grafts have had a great improvement due to many factors. Careful preoperative evaluation in transplant recipients, experience and a multidisciplinary approach have, without any doubt, a major role in the selection of candidates and in the diagnosis and treatment of preoperative complications. Moreover, with the introduction of...

متن کامل

Renal dysfunction after orthotopic heart transplantation: incidence, natural history, and risk factors.

BACKGROUND Renal dysfunction is a common complication after orthotopic heart transplantation (HT). The importance of factors other than exposure to immunosuppressive drugs is unclear. The purpose of this study was to determine the incidence and natural history of renal dysfunction following heart transplantation, and to evaluate a number of variables as risk factors for this condition. METHOD...

متن کامل

Risk factors and treatments for hepatic arterial complications in pediatric living donor liver transplantation.

BACKGROUND Hepatic artery complications (HAC) are a serious complication in pediatric liver transplant recipients because its incidence is high and it can occasionally lead to graft liver failure. We herein present a retrospective analysis of our 10-year experience with pediatric living donor liver transplantation (LDLT) focusing on the risk factors and treatments for HAC. METHODS Between May...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}

  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

دانلود متن کامل

برای دسترسی به متن کامل این مقاله و 23 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید


عنوان ژورنال:

دوره 4  شماره 3

صفحات  1529- 1544

تاریخ انتشار 2016-03-01

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2022