Study and Evaluation of Formulation and Nutritional values of parenteral Nutrition Formulae of Iranian Generic Project in Ten Major General Hospitals

Abstract: Parenteral Nutrition Formulae in Iranian Generic Project were studied in 31 patients hospitalized in ten major general hospitals in Tehran and Shiraz. Estimated theoretical energy (Calculated Energy Value or CEE) using Harris- Benedict equations and applying the Cerra stress factor was compared with the amount of energy estimated via indirect calorimetric technique (Measured Energy Expenditure or MEE) and following results were drawn: 1 - In view of variation in energy expenditure between males and females, it is necessary to apply two different formulae in calculating the amount of energy expenditure, as it is introduced by Harris- Benedict equations for determination of basal energy expenditure (BEE). 2- Results derived from application of two methods of measurements in determination of energy expenditure (theoretical and experimental methods) were comparable. Thus, it is possible to apply two different methods in measurement of energy expenditure of patients. 3- Although, Cerra stress factor which is applied in theoretical estimate of energy expenditure of patients, is significantly different from true factor (MEE/ BEE), nevertheless.it has a relative validity for estimation of energy expenditure. 4- Formulae used in Iranian Hospitals under present investigation for parenteral nutrition seem to be relatively sufficient for the purpose of provision of patients nutritional needs. However it is recommended that a variety of dextrose formulae in the range of 5-70 percent and other amino acid formulae similar to synthamin and Aminoplex to be supplied in Iranian Generic project. 5- It is strongly recommended that nutrition support teams, comprising of a physician (preferebly a surgeon), a pharmacist. a nurse and a nutritional care specialist, to be established in major Iranian Hospitals in order to assist the management of parenteral nutrition