Alcoholic extracts of the rhizomes of Alpinia galanga, Andrographis paniculata, bark of Cinnamomum zeylanicum, rind of Citrus decumana, Desmodium triflorum, seeds of Hydnocarpus wightiana, rhizomes of Kaempfaria galanga, Lippia nodiflora, tender leaves of Morinda citrifolia, rhizomes of Pollia serzogonian, Tephrosia purpuria and rhizomes of Zingiber zerumbeth showed good in vitro anthelmintic a...

An effective vacuum assisted extraction (VAE) technique was proposed for the first time and applied to extract bioactive components from Andrographis paniculata. The process was carefully optimized by response surface methodology (RSM). Under the optimized experimental conditions, the best results were obtained using a boiling temperature of 65 °C, 50% ethanol concentration, 16 min of extractio...

Andrographis paniculata (Nees), is a valuable traditional medicinal plant and it has many important bioactive compounds. It cures and prevents a number of diseases in human beings. It is a boon of the nature of human healthy life. It cures cold, fever, colic pain, active against inflammatory, antidiabetic activity, antioxidant, antifertility, cardiovascular and anti-virus including inhibited HI...

Objective: The present investigation addresses the inhibitory potential of five Andrographis paniculata (AP) extracts of different polarity and its three active constituents on UGT1A1, UGT1A4 and UGT2B7. Methods: Bioluminescent assay with luciferin as a substrate was used to determine IC50 values for all extracts and constituents. The kinetic enzyme inhibition experiments were subsequently perf...