Hellenic Journal of Nuclear Medicine • September December 2009 291 To the Editor: The Hell J Nucl Med has printed an article comparing technetium-99m pentavalentdimercapto succinic acid (99mTc(V)-DMSA) as an effective agent diagnosing acute bone and joint infection [1]. We now report that 99mTc(V)-DMSA can identify foci of infection in a case of fever of unknown origin. 99mTc(V)-DMSA, as a tumo...

BACKGROUND The lead mobilization test reflects the mobilizable and likely toxicologically active fraction of the lead body burden. We propose a safe and convenient protocol for this test, to assess concomitant copper and zinc excretion and to determine the size of the chelatable lead pool in nonoccupationally exposed adults. METHODS The study population included 80 white adults: 40 controls [...

In this study an attempt has been made to examine the efficacy of meso-2,3-dimercaptosuccinic acid (DMSA) using galactosylated liposomes as carriers for mobilization of cadmium from the body of mice preexposed to cadmium chloride (0.005 mmoles/kg intraperitoneally daily for 4 days). Cadmium-exposed mice after a rest period of 8 weeks were administered DMSA intravenously, two injections 15 micro...

BACKGROUND Bardet-Biedl syndrome (BBS) is a multisystem genetic disorder characterized with central obesity, pigmentary retinopathy, polydactyly, mental retardation, and hypogenitalism. Renal abnormalities have been recognized as a cardinal feature of the disease with serious prognostic implication. The aim of this study was to analyze the renal status in children with BBS and to implement appr...

© 2008 Elsevier. All rights reserved. The pentavalent Tc-99m dimercaptosuccinic acid (Tc99m (V) DMSA, Tc(V)-DMSA) radiotracer has become more widely used. The accumulation of Tc(V)-DMSA in tumors was first reported in 1981 [1], and this tracer has subsequently been shown to localize in a variety of tumors [2,3]. Tc(V)-DMSA has also been used to depict abscesses and other inflammatory lesions [4...

Tc-99m dimercaptosuccinic acid (DMSA) is used as a renal cortical imaging agent to detect parenchymal abnormalities especially in children. Kidney uptake of DMSA provides an index for evaluation of a functional tubular mass, which depends on the renal blood flow and proximal tubular cell membrane transport function. We here report a boy with renal tubular acidosis, which has noticeably reduced ...

background: diagnosis of kidney scar could prevent vesico urethral reflax and its complications such as hypertension and renal failure. this study was conducted to determine average kidney length and volume in infants by sonography to accurate diagnosis of scars. methods: this study was conducted on infants with the history of uti who referred to imam reza hospital, kermanshah iran, for dmsa sc...

OBJECTIVE The aim of this study was to compare the renal function measured with either 99mTc-DTPA or 99mTc-EC dynamic scintigraphies with that measured using 99mTc-DMSA static scintigraphy. METHODS the values of relative renal function measured in 111 renal dynamic scintigraphies performed either with 99mTc-DTPA (55 studies) or with 99mTc-EC (56 studies) were compared with the relative functi...

The system specific chaperone DmsD plays a role in the maturation of the catalytic subunit of dimethyl sulfoxide (DMSO) reductase, DmsA. Pre-DmsA contains a 45-amino acid twin-arginine leader peptide that is important for targeting and translocation of folded and cofactor-loaded DmsA by the twin-arginine translocase. DmsD has previously been shown to interact with the complete twin-arginine lea...