Primary headache disorders such as migraine affect almost a third of women during their childbearing years, when decisions about contraception must be made. Headache is also a commonly reported adverse event in clinical trials of oral contraceptives (OCs). Health care practitioners will frequently be called upon to give advice about the use of OCs to women with headache. This article applies cu...

Chronic craniofacial pain involves the head, face and oral cavity and is associated with significant morbidity and high levels of health care utilization. A bidirectional relationship is suggested in the literature for poor sleep and pain, and craniofacial pain and sleep are reciprocally related. We review this relationship and discuss management options. Part I reviews the relationship between...

Abstract Introduction The role of testosterone therapy (TTH) in men with prostate cancer (PC) is debated, especially on active surveillance (AS). Objective This study aimed to review our data TTH this population. Methods population consisted (i) PC (ii) two total T (TT) levels <300 ng/dL (iii) associated symptoms performed using LCMS (v) conducted an early morning fashion who (vi) pursue...

Abstract Background There have been several calls for estimations of costs and consequences headache interventions to inform European public-health policies. In a previous paper, in the absence universally accepted methodology, we developed headache-type-specific analytical models be applied implementation structured services Europe as health-care solution headache. Here apply this methodology ...

Headache(TTH). The headache is associated with vestibular impairment (VI) and neck pain, but this association has not been studied in elder population. Objective: To determine the of common types headaches pain elderly. Methods: A cross sectional study was conducted from February 2021 to June at District Headquarters Hospital Narowal using a non-probability convenience sampling technique on n=1...

The requirement for Watson-Crick base pairing surrounding a nick in duplex DNA to be sealed by DNA ligase is the basis for oligonucleotide ligation assays that distinguish single base mutations in DNA targets. Experiments in a model system demonstrate that the minimum length of oligonucleotide that can be joined differs for different ligases. Thermus thermophilus (Tth) DNA ligase is unable to j...

We consider a Maker-Breaker type game on the square grid, in which each player takes t points on their tth turn. Maker wins if he obtains n points on a line (in any direction) without any of Breaker’s points between them. We show that, despite Maker’s apparent advantage, Breaker can prevent Maker from winning until about his nth turn. We actually prove a stronger result: Breaker only needs to c...