نتایج جستجو برای: اوپیوییدها opioids

تعداد نتایج: 9792  

Journal: :MMWR. Morbidity and mortality weekly report 2016
Macarena C García Anton B Dodek Tom Kowalski John Fallon Scott H Lee Michael F Iademarco John Auerbach Michele K Bohm

Overdose deaths involving opioid pain medications are epidemic in the United States, in part because of high opioid prescribing rates and associated abuse of these drugs (1). In 2014, nearly 2 million U.S. residents either abused or were dependent on prescription opioids (2). In Massachusetts, unintentional opioid-related overdose deaths, including deaths involving heroin, increased 45% from 20...

Journal: :British journal of pharmacology 2015
H Reinecke C Weber K Lange M Simon C Stein H Sorgatz

UNLABELLED Opioids are regularly administered in acute and cancer pain. In chronic non-cancer pain (CNCP), however, their use is controversial. Previous meta-analyses and randomized controlled trials (RCTs) lack methodological homogeneity and comparable data. Here we analysed the maximum analgesic efficacies of opioids and non-opioids compared with placebo, and of physiotherapy and psychotherap...

Journal: :Pain 2004
Eija Kalso Jayne E Edwards R Andrew Moore Henry J McQuay

Opioids are used increasingly for chronic non-cancer pain. Controversy exists about their effectiveness and safety with long-term use. We analysed available randomised, placebo-controlled trials of WHO step 3 opioids for efficacy and safety in chronic non-cancer pain. The Oxford Pain Relief Database (1950-1994) and Medline, EMBASE and the Cochrane Library were searched until September 2003. Inc...

Journal: :British Journal of Anaesthesia 1990

Journal: :Journal of Pain and Symptom Management 2001

Journal: :Journal of Pain & Palliative Care Pharmacotherapy 2018

Journal: :Annals of Oncology 2008

2015
Tomohiko Aoe

Opioids like morphine have been widely used clinicaly as effective analgesics for acute and chronic pain. When opioids are used, the importance of care for side effects such as nausea, drowsiness and constipation is emphasized. In addition, continuous use of opioids developes tolerance in which the analgesic effect becomes attenuated. In this paper, we mainly discuss endoplasmic reticulum (ER) ...

Journal: :Anaesthesia and Intensive Care 1987

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