Glycoprotein G (gG) of alphaherpesviruses has been described to function as a viral chemokine binding protein (vCKBP). More recently, mutant viruses devoid of gG have been shown to result in increased virulence, but it remained unclear if gG's potential to serve as a vCKBP is responsible for this observation. We here used equine herpesvirus type 1 (EHV-1) as a model to study the pathophysiologi...

Equine herpesvirus 1 (EHV-1) is a major pathogen affecting equines worldwide. The virus causes respiratory disease, abortion, and, in some cases, neurological disease. EHV-1 Kentucky A (KyA) is attenuated in the mouse and equine, whereas wild-type pathogenic strain RacL11 induces severe inflammatory infiltration of the lung, causing infected mice to succumb. The complete DNA sequencing of the K...

Equine herpesvirus type 1 (EHV-1) causes respiratory disease, abortion and neurological disorders in horses. Besides epithelial cells, CD172a+ monocytic cells become infected with EHV-1 in the respiratory mucosa and transport the virus from the apical side of the epithelium to the lamina propria en route to the lymph and blood circulation. Whether CD172a+ monocytic cells are specifically recrui...

the main objective of this study was to estimate the seroprevalence of bovine herpes virus type 1 and parainfluenza type 3 in a non-vaccinated population cattle in the livestock region of qazvin province. totally 504 sera were randomly collected and tested from 8 industrial dairy farms in qazvin province during march 2010-march 2011. the result of one way analysis of variance was used for th...

Bovine herpesvirus type 1 (BoHV-1) causes respiratory and reproductive disorders in cattle. Recently, bovine herpesvirus type 5 (BoHV-5) and bovine herpesvirus type 4 (BoHV-4) have been identified to be associated with genital disease. In this study, the presence of the genome of BoHV-1, BoHV-4 and BoHV-5 in bovine semen of Argentinean and international origin was analyzed by PCR assays. The mo...