tumor necrosis factor -alpha (tnfα) is a proinflammatory cytokine that plays critical roles in the regulation of immune responses including macrophages activity and apoptosis. tnfα gene is polymorphic and its haplotypes have been associated with resistance or susceptibility to disease. this study was undertaken to identify the polymorphism of tnfα gene in makoei sheep, using polymerase chain re...

Repair of DNA damage is essential to the preservation of genomic stability. During repair of double-strand breaks, several helicases function to promote accurate repair and prevent the formation of crossovers through homologous recombination. Among these helicases is the Fanconi anemia group M (FANCM) protein. FANCM is important in the response to various types of DNA damage and has been sugges...

Objectives: A cartilage degradation product, the Fibronectin-Aggrecan complex (FAC), has been identified in patients with degenerative disc disease (DDD). Alpha-2-macroglobulin (A2M) can prevent the formation of the G3 domain of aggrecan, reducing the fibronectin-aggrecan G3 complex and therefore may be an efficacious treatment. The present study was designed to determine a. The ability of auto...

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Abstract Introduction A polysomnography or home sleep apnea study provides multiple pieces of information to diagnose obstructive (OSA), but the tests are costly with limited access. The aims use an automated AHI model only PPG signals and can be applied a wearable device. Methods We have included patients different OSA severity build algorithm detecting ODI based on scoring criteria varying si...

AIM To assess the correlation of lateral recess stenosis (LRS) of lumbar segments L4/5 and L5/S1 and the Oswestry Disability Index (ODI). METHODS Nine hundred and twenty-seven patients with history of low back pain were included in this uncontrolled study. On magnetic resonance images (MRI) the lateral recesses (LR) at lumbar levels L4/5 and L5/S1 were evaluated and each nerve root was classi...

BACKGROUND The vacuum phenomenon within the intervertebral disc usually represents disc degeneration. There are no reports in the English literature that focus on the effect of an anterior vacuum disc on surgical outcome of same-segment spondylolisthesis. METHODS Patients with degenerative spondylolisthesis (DS) or isthmic spondylolisthesis (IS) who underwent a spinal surgery between January ...

STUDY DESIGN A nation-wide, outpatient-based, cross-sectional survey with the use of questionnaires. PURPOSE To evaluate the pain, disability and satisfaction of patients with osteoporotic vertebral compression fractures (OVCFs). OVERVIEW OF LITERATURE There are no nation-wide data in Korea on the degree of pain, disability and satisfaction with treatment in patients with OVCFs. METHODS W...

PURPOSE The purpose of this study was to analyze the clinical and radiological results of repair of the interarticularis pars defect by a modified Buck's repair technique in patients with symptomatic spondylolysis with grade 1 spondylolisthesis. These patients with painful spondylolisthesis are the most eligible for direct repair of the defect rather than lumbo-sacral fusion in an attempt to sa...