INTRODUCTION Acne vulgaris is a pilosebaceous gland disease that usually affects people from puberty to young adulthood. It is seen especially on the face, neck, trunk and arms. Its severity differs from patient to patient and its pathogenesis is multifactorial. The main pathogenic factors of acne are high sebaceous gland secretion, follicular hyperproliferation, high androgen effects, propioni...

BACKGROUND Although, melasma is most prevalent among Asian young women, and also darkly pigmented individuals are particularly prone to developing post inflammatory hyperpigmentation, to the best of our knowledge, there are rare or no studies about the association of melasma and Post inflammatory hyperpigmentation. OBJECTIVES The aim of this study was to investigate how likely is a melasma pa...

BACKGROUND Vitamin D plays an important role in the immune system, and its deficiency has been implicated in various skin diseases, including atopic dermatitis and psoriasis. Acne is a common inflammatory skin disease; however, the association with vitamin D remains unclear. OBJECTIVES We evaluated vitamin D levels in patients with acne to determine the effect of vitamin D supplementation. ...

Background: The studies on Acne vulgaris conducted in many parts of the world show that it is very common in adolescents but little is known from Nepal. Objectives: To assess knowledge and attitude regarding Acne vulgaris among school students. Methods and Materials: This was a descriptive study conducted among 100 students of class 9 & 10 of Kumudini Homes Higher Secondary School, Pokhara, Nep...

Acne vulgaris as an inflammatory disease, with an excessive production of subdermal fat, modifies the dynamics of the bloodstream, and consequently temperature, on the affected skin zone. A high percentage of this heat interchange is manifested as electromagnetic radiation with far-infrared wavelengths, which can be captured through a thermal imaging camera. A technique based on thermal image a...

BACKGROUND Systemic and topical antimicrobials are effective in the treatment of inflammatory acne vulgaris; however, widespread use of these agents is becoming increasingly associated with the emergence of resistant pathogens raising concerns about microorganism resistance and highlighting the need for alternative nonantimicrobial agents for the treatment of acne. Nicotinamide gel provides pot...

Acne vulgaris is a common inflammatory skin condition. Although often perceived as a self limited disease of adolescence, its prevalence remains high into adulthood. Nearly 90% of teenagers have acne, and half of them continue to experience symptoms as adults. By age 40 years, 1% of men and 5% of women still have lesions. Recent analyses show an increasing prevalence of acne in children, perhap...

Acne is one of the most common skin disorders. It is a multifactorial and complex disease, originating in the pilosebaceous follicle where a hereditary background, androgens, skin lipids, disorders of keratinization, inflammatory signaling, and regulatory neuropeptides seem to be mainly involved. Even though emotional stress has long been suspected to trigger or exacerbate acne, its influence o...

Acne vulgaris is a common dermatological disorder with a multifactorial pathogenesis. Oxidative status has been implicated in the pathogenesis of several skin diseases, including acne. This study was aimed to investigate the levels of oxidative stress biomarkers in acne vulgaris patients with varying severities. The study involved 156 patients with acne and 46 healthy human controls. Based on c...

OBJECTIVE To quantitatively document the presence and extent of a late luteal (premenstrual) acne flare in adult women. DESIGN Case series. SETTING Subjects were recruited from a general community dermatology practice and by advertising. SUBJECTS Adult women 18 to 44 years old with normal periods who were receiving no treatment for their acne. MAIN OUTCOME MEASURES Acne lesion counts we...