نتایج جستجو برای: intracerebroventricular injection

تعداد نتایج: 159066  

Journal: :Hypertension 2007
Ranjita J Kokje Wendy L Wilson Travis E Brown Vardan T Karamyan John W Wright Robert C Speth

UNLABELLED Intracerebroventricular administration of angiotensins causes pronounced pressor and dipsogenic responses. The suggestion that angiotensin III rather than angiotensin II is the active peptide in the brain spawned what we call The Angiotensin III. HYPOTHESIS To test this hypothesis, 5 angiotensin II analogs containing zero or one position substitutions conferring resistance to amino...

2005
Tomohiro Chiba Marina Yamada Yuichi Hashimoto Maiko Sato Jumpei Sasabe Yoshiko Kita Kenzo Terashita Sadakazu Aiso Ikuo Nishimoto Masaaki Matsuoka

Alzheimer’s disease (AD) is the most common cause of dementia. Humanin (HN) is a short bioactive peptide abolishing neuronal cell death induced by various familial AD (FAD)-causative genes and amyloid(A ) in vitro. It has been shown that HN suppresses memory impairment of mice induced by intracerebroventricular administration of A . To potentiate the neuroprotective effect of HN, we synthesized...

Journal: :iranian journal of veterinary medicine 2010
ali zanboori esmaeil tamadon fard ali mojtahedin

in the present study, the effects of intracerebroventricular (icv) injections of histamine, chlorpheniramine (h1-receptor antagonist) and ranitidine (h2-receptor antagonist) were investigated on visceral nociception induced by an intraperitoneal (ip) injection of acetic acid in rats. the latency time to the beginning of the first abdominal wall contraction (the first writhe) was recorded and th...

2011
Jae Geun Kim Byong Seo Park Chang Ho Yun Hyun Jun Kim Sang Soo Kang Angela Valentina D’Elia Giuseppe Damante Ki-Up Lee Jeong Woo Park Eun Sook Kim Il Seong Namgoong Young Il Kim Byung Ju Lee

OBJECTIVE α-Melanocyte-stimulating hormone (α-MSH) and agouti-related peptide (AgRP) control energy homeostasis by their opposing actions on melanocortin receptors (MC3/4R) in the hypothalamus. We previously reported that thyroid transcription factor-1 (TTF-1) controls feeding behavior in the hypothalamus. This study aims to identify the function of TTF-1 in the transcriptional regulation of Ag...

ژورنال: پژوهش در پزشکی 2012
پوزش, ریحانه, خواجه دلوئی, محمد رضا , واعظی, غلامحسن ,

Abstract Background: Fear is an emotional response to threat or danger and is often associated with behavioral and physiological disorders. Pathological fear remains with the person for a long time. Herbal medicine is the oldest form of treatment and has long been used for combating fear. This research was performed on adult male rats to study the effect of Elettaria cardamomum seed on fear....

Ali Asghar Pilehvarian Hamid Azizi Malekabadi Hamid Reza Dehghani Dolatabadi Hojjatallah Alaei Parham Reisi,

Objective(s) The present study aimed to investigate the effects of a fat soluble antioxidant, coenzyme Q10 (CoQ10) and folic acid on learning and memory in the rats with intracerebroventricular injection of streptozotocin (ICV-STZ), an animal model of sporadic type of Alzheimer's disease. Materials and Methods The lesion groups were injected bilaterally with ICV-STZ (1.5 mg/kg b.wt., in norm...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2003
Ling Lin Sonjya R Thomas Gail Kilroy Gary J Schwartz David A York

Enterostatin, a pentapeptide released from the exocrine pancreas and gastrointestinal tract, selectively inhibits fat intake through activation of an afferent vagal signaling pathway. This study investigated if the effects of enterostatin were mediated through a CCK-dependent pathway. The series of in vivo and in vitro experiments included studies of 1) the feeding effect of peripheral enterost...

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