نتایج جستجو برای: lag classification
تعداد نتایج: 513196 فیلتر نتایج به سال:
We describe a novel spontaneous mouse mutant, laggard (lag), characterized by a flat head, motor impairment and growth retardation. The mutation is inherited as an autosomal recessive trait, and lag/lag mice suffer from cerebellar ataxia and die before weaning. lag/lag mice exhibit a dramatic reduction in brain size and slender optic nerves. By positional cloning, we identify a splice site muta...
Lymphocyte activation gene-3 (LAG-3; CD223), a structural homolog of CD4, binds to MHC class II molecules. Recent research indicated that signaling mediated by LAG-3 inhibits T cell proliferation, and LAG-3 serves as a key surface molecule for the function of regulatory T cells. Previous reports demonstrated that the majority of LAG-3 is retained in the intracellular compartments and is rapidly...
BACKGROUND More invasive retinoblastoma, characterized by increased morbidity and mortality, with lower rates of eye salvage and higher rates of extraocular dissemination, seems more prevalent in resource-poor countries. The relationship of diagnostic delay (lag time) and sociodemographic factors on the extent of disease at diagnosis has not been examined separately for unilateral and bilateral...
ABSTRACT Much researches has focused on the theory that antioxidant nutrients act as scavengers of oxygen derived free radicals, thereby helping to prevent cell and tissue damage that otherwise would give rise to degenerative diseases such as atherosclerosis caused by LDL oxidation. Findings from extensive studies suggested that the determination of lag objective procedure for determining the ...
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