OBJECTIVE This study investigated the expression and prognostic significance of the CD95 death receptor and CD20, a B cell-lineage associated marker, along with CD34 and CD44 non-lineage associated molecules in Iranian children with acute lymphoblastic leukemia (ALL). METHODS We performed immunophenotyping for expressions of the molecules in blood samples from children diagnosed with ALL by u...

BACKGROUND Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a clinically and genetically distinct and uncommon variant of SMA that results from irreversible degeneration of α-motor neurons in the anterior horns of the spinal cord and in ganglion cells on the spinal root ganglia. AIMS To describe the clinical, electrophysiological, neuropathological, and genetic findings, a...

BACKGROUND Negative T (NT) wave in electrocardiography (ECG) is one of the important factors in determining short- and long-term outcomes in patients with acute myocardial infarction (MI). In this study, we compared clinical and paraclinical findings in post-MI patients according to presence or absence of NT wave. METHODS A cross-sectional study was conducted on patients with acute ST elevati...

pheochromocytoma is a catecholamine‑producing tumor. there are a very few reported cases of clinical pheochromocytoma. here, we report a 27‑year‑old woman para 1 live 1 with chief complaint of headache, confusion, nausea, and vomiting 2 days after cesarean section. she was anxious and had palpitation. on physical examination, fever, tachycardia, tachypnea, high blood pressure, and right thyroid...

behcet's disease (bd) is a multisystemic inflammatory disease that occurs most often between the second and fourth decade of life. patients have been reported during the first months of life and after 70 years. our objective was to determine the clinical, paraclinical and genetic characteristics of bd in patients aged < 20 and > 40 years. we conducted a comparative retrospective study including...

The localized form of pigmented villonodular synovitis of the knee is a rare condition with non-specific symptoms. This makes diagnosis especially difficult when the meniscus is affected. A full assessment with several imaging modalities can help support the preoperative diagnosis. But in the case reported here, the full clinical and paraclinical assessment (X-rays, CT arthrography and MRI) was...

Neuromyelitis optica (NMO) is a rare and severe inflammatory disease of the central nervous system (CNS), which constitutes up to 5% of pediatric aquired demyelinating diseases. The optic nerves and the spinal cord are the most affected sites. The discovery of an autoantibody called NMO-IgG, which targets aquaporin-4, the main water channel in the CNS, gave a new direction to understanding the ...

The Monteggia fracture is one of the pitfalls of conventional diagnosis of upper limb trauma. Through a retrospective study of 20 cases diagnosed at the Department of Orthopaedic Surgery and Traumatology, University Hospital Center, Ibn Sina, Mohamed V University, Rabat, Morocco, between 2010 and 2014, we have tried to do an update on the management of Monteggia fractures either at of paraclini...