We present a new Integrated Finite Element Neural Network framework (I-FENN), with the objective to accelerate numerical solution of nonlinear computational mechanics problems. leverage swift predictive capability neural networks (NNs) and we embed them inside finite element stiffness function, compute element-level state variables their derivatives within nonlinear, iterative solution. This pr...

• An extended non-local formulation for dynamic explicit simulations. Three dimensional parallel Identification and validation based on simulation-experiment comparisons. Comparison between the implicit gradient micromorphic approaches. In automotive industry, crack prediction is an important step of design: its accuracy crucial to avoid additional development costs delays. However, simulation ...

Although electrosurgical instruments are widely used in surgery to cut tissue layers or to achieve hemostasis by coagulation (electrocautery), only little information is available concerning the inflammatory or immune response towards the debris generated. Given the elevated local temperatures required for successful electrocautery, the remaining debris is likely to contain a plethora of compou...

To minimize oxidative damage to the cell, malfunctioning mitochondria need to be removed by mitophagy. In neuronal axons, mitochondrial damage may occur in distal regions, far from the soma where most lysosomal degradation is thought to occur. In this paper, we report that PINK1 and Parkin, two Parkinson's disease-associated proteins, mediate local mitophagy of dysfunctional mitochondria in neu...

The hypothesized advantages of cryosurgery include improved local control and benefits common to any minimally invasive procedure (e.g., preserving normal organ tissue, decreasing morbidity, decreasing length of hospitalization). Potential complications of cryosurgery include those caused by hypothermic damage to normal tissue adjacent to the tumor, structural damage along the probe track, and ...

Wildlife damage to crops is a widespread concern among agricultural producers and wildlife professionals. In the United States, raccoon (Procyon lotor) damage to field corn (Zea maize) has become a serious concern, as raccoon depredation to corn has increased significantly in recent years. However, little information is available to suggest the underlying factors responsible for recent increase...

We investigate compressive failure of heterogeneous materials on the basis of a continuous progressive-damage model. The model explicitly accounts for tensile and shear local damage and reproduces the main features of compressive failure of brittle materials like rocks or ice. We show that the size distribution of damage clusters, as well as the evolution of an order parameter--the size of the ...