Deposition of β-amyloid (Aβ), a 'signature' pathological lesion of Alzheimer's disease (AD), is also characteristic of Down's syndrome (DS), and has been observed in dementia with Lewy bodies (DLB) and corticobasal degeneration (CBD). To determine whether the growth of Aβ deposits was similar in these disorders, the size frequency distributions of the diffuse ('pre-amyloid'), primitive ('neurit...

OBJECTIVE To evaluate whether otosclerosis is an underlying mechanism for the production of cupular deposits and to study the association between cupular deposits and dysequilibrium in otosclerosis. DESIGN Retrospective human temporal bone (TB) study. The incidence of cupular deposits in these 70 TBs was analyzed. Correlations between cupular deposits and vestibular symptoms, endosteal involv...

Nonglacial deposits Artificial fill (Holocene)—Mud, sand, and gravel of varying proportions, possibly including foreign debris such as concrete, logs, timbers, or brick. Used for highway roadbeds and other construction. Thickness generally greater than 2 m. Mapped where fill substantially obscures or has altered original geologic deposit. Beach deposits (Holocene)—Soft sand, silt, and mud depos...

A number of voluminous, fine-grained, friable deposits have been mapped on Mars. The modes of origin for these deposits are debated. The feasibility for an origin by volcanic airfall for the friable deposits is tested using a global circulation model to simulate the dispersal of pyroclasts from candidate source volcanoes near each deposit. It is concluded that the Medusae Fossae Formation and E...

Identification of sea-level proxies is important for reconstruction of past sea-level variation. Methods for reconstructing Holocene relative sea-level curves are crucial for quantification of the impact of Greenland ice thickness variation on global sea level and vertical land movement. Arctic beach ridges constitute important potential archives of sea-level variation. However, their surface m...

The lack of fossil tetrapod bearing deposits in the earliest Carboniferous ('Romer's Gap') has provoked some recent discussions regarding the proximal cause, with three explanations being offered: environmental, taphonomic, and collection failure. One of the few, and earliest, windows into this time is the locality of Blue Beach exposed in the Tournaisian deposits at Horton Bluff lying along th...

Tephra is a product of large and explosive volcanic events and can travel thousands of kilometers before deposition. Consequently, tephra deposits are common in terrestrial, lacustrine, marine, and glacial environments. Because tephra deposition is a geologically synchronous event, tephras constitute important isochrones in the Quaternary sequence, not only in Japan but also throughout the nort...

Plant macrofossils and pollen play complementary roles in paleoecology. Each has its own advantages and shortcomings. Used separately, they provide valuable information about past vegetation. Used together, the two types of data can corroborate or, occasionally, challenge each other, and they can provide more detailed and refined understanding of past vegetation at multiple spatial scales. In t...

OBJECTIVE To assess clinicopathological characteristics of lupus nephritis patients with scanty immune deposits. METHODS The data of patients with scanty immune deposits lupus nephritis were retrospectively analyzed. Plasma ANCA and complement components were detected. RESULTS Among 316 cases with renal biopsy-proven lupus nephritis, 40 cases were diagnosed as scanty immune deposits. There ...