Since fiscal year 1991, the U.S. Human Genome Project has spent $170.6 million in federal funds to help isolate genes associated with Huntington's disease, amyotrophic lateral sclerosis, neurofibromatosis types 1 and 2, myotonic dystrophy, and fragile X syndrome and to localize genes that predispose people to breast cancer, colon cancer, hypertension, diabetes, and Alzheimer's disease. Now come...

The lack of social responsibility in megaproject has been frequent recent years, causing serious waste resources and posing a huge governance problem for the sustainable development such projects. In order to solve this challenge, an in-depth study reasons is needed. This paper constructs stakeholder network model with "positive" (better fulfillment responsibility) "negative" (lack dimensions b...

a r t i c l e i n f o Aims: The paper reviews the development of information and communication technology in briefing and proposes a collaborative briefing framework to extend key stakeholder engagement, aiming to improve the efficiency and reliability of project briefing for megaprojects. Scope: Authors introduce an innovative collaborative approach to promote stakeholder involvement by enhanc...

Purpose: Rapid worldwide growth in megaprojects has attracted academic interest. In practice, complexity is one of the main causes for failure megaprojects. This study proposes a system project manager leadership to overcome problems achieving success with megaproject.Design/methodology/approach: uses configuration analysis, fuzzy-set qualitative comparative analysis (fsQCA), investigate combin...

The vast sums of money involved in megaprojects, and the perceived lack public benefit, create controversy. Flyvberg’ s iron law asserts that megaprojects are over budget, time, under benefits, again (Flyvberg, 2018). More recent research suggests this focus on cost overruns is based highly misleading data (Love & Ahiaga-Dagbui, 2017). This seeks to examine live Flyvbjergs theories practice...