I read the article titled " Fine needle diathermy – A choice for managing corneal vascularization " and written by Thatte S (2011) with great interest as corneal vascularization is a very common problem encountered by us also in Nepal. Most of the cases that we see are healed corneal ulcers with vascularization, in which doing an optical keratoplasty is a big challenge. The author has done a ve...

The transcription factor TBX1 is the major gene involved in 22q11.2 deletion syndrome (22q11.2DS). Using mouse models of these diseases, we have previously shown that TBX1 activates VEGFR3 in endothelial cells (EC), and that this interaction is critical for the development of the lymphatic vasculature. In this study, we show that TBX1 regulates brain angiogenesis. Using loss-of-function genetic...

Current methods for engineering vascularized tissues rely primarily on the self-organization of vascular cells (endothelial cells, pericytes, and smooth muscle cells) or their progenitors in a scaffold and/or on the recruitment of new vessels via release of angiogenic factors [1,2]. While these approaches certainly accelerate the process of graft vascularization, they still require several days...

Hyperplasia of the endometrial stroma is a poorly recognized lesion, lacking widespread recognition with most, if not all, such cases sequestrated in the literature as endometrial stromal nodules or low-grade endometrial stromal sarcomas. In this paper, we describe three examples of "endometrial stromal hyperplasia" which have a remarkable morphological similarity with the normally proliferatin...

background: many studies have been carried out to understand the effect of endometrial thickness on the reproductive outcome while the factors affecting the pattern itself are still unknown. objective: to determine the factors such as age and the number of follicles that could affect the endometrial thickness materials and methods: this study was conducted as a retrospective study on 680 infert...

Background: The aim of this study was to investigate the percentage of the stem cells population in human endometrial tissue sections and cultured cells at fourth passage. Methods: Human endometrial specimens were divided into two parts, one part for morphological studies and the other part for in vitro culture. Full thickness of human normal endometrial sections and cultured endometrial cells ...

OBJECTIVE To determine if power Doppler ultrasound examination of the endometrium can contribute to a correct diagnosis of endometrial malignancy in women with postmenopausal bleeding and endometrium > or = 5 mm. METHODS Eighty-three women with postmenopausal bleeding and endometrium > or = 5 mm underwent gray-scale and power Doppler ultrasound examination using predetermined, standardized se...

OBJECTIVE To measure the diagnostic accuracy of endometrial thickness for the detection of intra-uterine pathologies among asymptomatic postmenopausal women, and to test the diagnostic accuracy and appropriateness of performed hysteroscopies. STUDY DESIGN Prospective study of 268 asymptomatic postmenopausal women with endometrial thickness ≥4 mm referred to diagnostic hysteroscopy. The diagno...

In this paper we present several ODE systems encoding the most essential observations and assumptions about the complex hierarchical interactive processes of tumor neo-vascularization (angiogenesis). From experimental results we infer that a significant marker of tumor aggressiveness is the oscillatory behavior of tumor size, which is driven by its vascularization dynamics. To study the forces ...