نتایج جستجو برای: insulin expression and secretion
تعداد نتایج: 16981496 فیلتر نتایج به سال:
background and objectives this study was undertaken to evaluate the effect of the cultivated satureja khuzestanica essential oil (skeo) on activity and gene expression of hepatic gk in normal and diabetic rats. methods biochemical parameters such as glucose, insulin, and hba1c plasma levels and oral glucose tolerance test were all analyzed. the cultivated skeo was orally administered at diffe...
Background and Aim: Selective PDE3 inhibitors, via cyclic adenosine monophosphate (cAMP) accumulation increase cardiac contraction and augment glucose-induced insulin secretion. In this study, the effects of some synthetic methylquinolinone derivatives (MC1-MC10) on glucose-induced insulin secretion in rats' isolated Langerhans islets model were investigated. Materials and Methods: After...
Background & Aims: As B. persicum is used in treatment of diabetes, we aimed to study the effect of B. persicum seeds extract on level of insulin secretion from isolated islets of langerhans in male mouse.Materials & Methods: In this experimental study, adult male mice (NMARI) weighting 20-25g were purchased. Islets of langerhans were isolated by collagenase digestion method and were divided i...
To investigate the correlation between serum 25-hydroxyvitamin D3 and abnormal insulin secretion in patients with type 2 diabetes mellitus. Eight mellitus treated from January 2018 to November 2020 (observation group) another 80 healthy volunteers receiving physical examination same period (control were included. Fasting venous blood sample was collected detect D3, fasting glucose, glycosylated...
background leptin and adiponectin are two hormones, which are released from adipocytes in order to control energy expenditure. both hormones are also involved in glucose homeostasis through control of insulin secretion from pancreatic islets. since pdx1, pparγ, and foxm1 play important roles in islets function, it is essential to understand how these genes are regulated in the islets of langerh...
Background: Cardiomyopathy is one of adverse effects of diabetes that associated with cardiac muscle metabolism and function disruption. Exercise training decreases adverse effects of diabetes on heart by changing genes involved in cardiac metabolism and increasing myokines secretion. So, the aim of this study was to investigate of 8 weeks aerobic training on cardiac PGC-1α gene expression and ...
Objective(s): Arsenic, a toxic metal in drinking water and butyric acid (BA) is a free fatty acid found in many foods. These two can induce oxidative stress in some tissues. The present study investigated the protective effect of metformin against toxicity induced by Arsenic (As) and BA in isolated mice liver mitochondria and pancreatic islets. Materials and Methods: In this study, liver mitoch...
Background: Usually excess feeding in stored in the body as fat and leads to overweight. One of the causes of catching type 2 diabetes is obesity. Proinflammatory cytokines such as TNF- α and IFNγ can damageTnf- Α And Ifnγ By Peripheral Blood Mononuclear Cells Of Patients With Diabetes Mellitus Type Ii Admitted To Ganjavian Dezful Hospit insulin signaling in insulin-sens...
Background: Pancreatic islet transplantation is one of the most promising strategies for treating patients with type I diabetes mellitus.Objective: We aimed to assess the immunoisolation properties of the multilayer encapsulated islets using alginate-chitosan-PEG for immunoprotection and insulin secretion from the encapsulated islets induced under differe...
Background and purpose: Diabetes mellitus is a metabolic disorder characterized by hyperglycemia, impaired insulin secretion or peripheral insulin resistance. Today, many herbal medicines are used in treatment of diabetes. Recently anti-diabetic properties of resveratrol are reported in some studies, but none have evaluated its anti-neuropathy properties and its' effect on Sirt1 gene expression...
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