Xanthine oxidase plays crucial roles in the production of reactive oxygen species (ROS), and uric acid in blood which may lead to gout, one of the oldest known forms of arthritis amongst humans. Summer savory (Satureja hortensis L.) a medicinal/spice exhibits antioxidant activity, but unknown effects on xanthine oxidase activity. Here, for the first time, we examined the effects of S. hortensis...

This paper describes a preliminary assessment of the nutraceutical value of Amaranthus cruentus (A. cruentus) and Amaranthus hybridus (A. hybridus), two food plant species found in Burkina Faso. Hydroacetonic (HAE), methanolic (ME), and aqueous extracts (AE) from the aerial parts were screened for in vitro antioxidant and xanthine oxidase inhibitory activities. Phytochemical analyses revealed t...

Fennel, Foeniculum vulgare Mill. (Apiaceae) is an aromatic plant, with medicinal and culinary applications, widely naturalized worldwide, especially near the see coasts and riversides. Fennel has long been used in Iran as a traditional remedy against gout. The objective of our study was to uncover the scientific basis of this traditional gout therapy. Different plant parts were extracted by met...

Introduction: Rosa damascena mill L., well-known as Rose, has numerous pharmacological properties including antioxidant, antitussive, relaxant effect on tracheal chains, hypnotic, antibacterial and anti-HIV. Objective: The objective of the present study was to evaluate antioxidant and free radical scavenging activity of various extracts of Rose flower petals. Methods: Chloroform, acetone, ethan...

In order to understand the factors responsible for the potent antioxidant and radioprotecting ability of triphala, it has been evaluated for radical scavenging ability, xanthine oxidase inhibitory activity and phytochemical (phenolics) content. The radical scavenging experiments were carried out using fast reaction kinetic tools and the reactivity of triphala towards different radicals such as ...

The best described pharmacological property of flavonoids is their capacity to act as potent antioxidant that has been reported to play an important role in the alleviation of diabetes mellitus. Flavonoids biochemical properties are structure dependent; however, they are yet to be thoroughly understood. Hence, the main aim of this work was to investigate the antioxidant and antidiabetic propert...

Background: Xanthine Oxidase activity may increase plasma urates, superoxide radicals and hydrogen peroxide leading to gout, arthritis cancer. Allopurinol, a known inhibitor, is noted have various adverse effects. Many laboratories are in research projects find alternative inhibitors of XO including plant sources. Plants contain therapeutically effective agents. A. senegalensis, M. sapientum L ...

The HPTLC analysis, antioxidant, and antigout activity of Asparagus racemosus, Withania somnifera, Vitex negundo, Plumbago zeylanica, Butea monosperma and Tephrosia purpurea extracts were investigated. The chemical fingerprinting were carried out by high performance thin layer chromatography (HPTLC), antioxidant activity by ABTS, DPPH, FRAP radical scavenging assays, and antiogout activity by c...

The antioxidant activity of eight Egyptian propolis samples from different localities was evaluated by the antioxidative potential and capacity of the DPPH-ESR signal, superoxide anion generated in the xanthine-xanthine oxidase (XOD) system and low density lipoprotein (LDL) peroxidation assay. As, F, Is and D samples showed the highest antioxidative capacity and potential, respectively. The El,...