The new year is a time for goal setting, reflection, and new beginnings. Often, resolutions begin with self-improvements of the physical kind-losing weight, exercising, eating clean. These are important ideas and goals, although often difficult to sustain in part because sustaining is an implied element of each. Intentions are different than goals in the sense that an intention can be implement...

The purpose of this study was to establish a collagen determination method based on an isotope-labeled peptide as internal reference via high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS), and using the established evaluate degradation process collagen-based implants in vivo. specific (GPAGPQGPR) bovine type I identified with Orbitrap spectrometer. Then, quantification...

Kynurenic acid (KYNA) has been attributed many beneficial properties, such as antioxidant, antiproliferative, anti-inflammatory, and anti-obesogenic, it is believed to affect metabolism weight gain. A rapid simple HPLC-MS/MS method for the determination of kynurenic in honey developed. system allowed us perform analyzes without any special extraction or treatment samples. The study was carried ...

BACKGROUND The potent immunosuppressant mycophenolic acid (MPA) is metabolized to an inactive glucuronide (MPAG). The extent of metabolism varies among individuals, and the MPAG formed can be hydrolyzed to MPA and can displace MPA from serum albumin, creating a potential need to monitor both MPA and MPAG. METHODS After addition of the carboxybutoxy ether of MPA (MPAC) as internal standard, MP...