Recently there has been growing interest in an alternative to conventional oxygen therapy: the heated, humidified high flow nasal cannula oxygen therapy (HFNC). A number of physiological effects have been described with HFNC: pharyngeal dead space washout, reduction of nasopharyngeal resistance, a positive expiratory pressure effect, an alveolar recruitment, greater humidification, more comfort...

OBJECTIVE Actively heated, humidified high flow nasal cannula oxygen therapy (HFNC) is a new type of oxygen therapy. Because of its unique physiological effects, the clinical application is becoming more and more popular. This article is to summarize the physiological effects, clinical application and short comings of HFNC. Compared with conventional oxygen therapy, HFNC helps to improve oxygen...

Humification of oxygen prior to administration by nasal cannula is an expensive practice which has been justified on the basis that it improves the comfort of patients receiving supplemental oxygen therapy. Routine humidification of low-flow oxygen (less than or equal to 4 L/min) delivered by nasal cannula has recently been challenged based on theoretic grounds and on the results of a clinical ...

OBJECTIVES To conduct an in vitro evaluation of a humidified high-flow nasal cannula (HFNC) system at different flows, cannula sizes, and air leaks and also an in vivo analysis of mean end-expiratory esophageal pressure (EEEP) from nasal continuous positive airway pressure at 6 cm H(2)O (NCPAP+6) versus HFNC. STUDY DESIGN In the in vitro study, we measured HFNC system pressure and flow, with ...

The search for effective evidence-based management strategies for children hospitalized with acute viral bronchiolitis is filled with dark rabbit holes of potential benefit that, for the most part, have led right back to the beginning. Such has been the case for antiviral agents, bronchodilators, systemic and inhaled corticosteroids, and, most recently, nebulized hypertonic saline. A new tool i...