In this article we evaluated an important complication of pregnancy, the fetal growth restriction (IUGR). IUGR is defined as an estimated fetal weight of fetal abdominal circumference below the 10th centile measured by ultrasound according to local standards. We present the prenatal surveillance, the screening tests for late IUGR and the new diagnostic examinations, to establish the best preven...

BACKGROUND Growth factor-binding proteins influence the growth of infants starting in utero. Adaptation of the fetus to an adverse uterine environment is associated with changes in the growth hormone-growth factor-insulin axis. AIMS To evaluate serum levels of IGF-I and IGFBP-3 in small and appropriate for gestational age newborn infants. METHODS Fifty-four newborn infants, small (SGA, n=28...

Maternal starvation is a significant cause of intrauterine growth restriction (IUGR) in the world and increases the risk of infection in the neonate. We examined the effect of maternal starvation on Toll like receptor (TLR)4 expression in hepatic, splenic and intestinal tissues obtained from the adult IUGR offspring of prenatal calorie restricted rats. The hepatic TLR4 protein concentration was...

The feasibility and reproducibility of liver stiffness measurements using Supersonic Shear-wave Imaging (SSI) in preterm neonate have not been reported. Our aim was to determine if liver stiffness differs between intra-uterine growth restriction (IUGR) and appropriate for gestational age (AGA) preterm infants with/without cholestasis. We measured liver stiffness (in kPa) in 45 AGA and 18 IUGR p...

OBJECTIVE Elevated nucleated red blood cell (NRBC) count is introduced as a potential marker of intra-uterine growth restriction (IUGR). To investigate the probable association regardless of any known underlying disease, we aimed to study disturbances in NRBC count in infants experiencing idiopathic IUGR. MATERIALS AND METHODS Twenty three infants regarded IUGR without any known cause were ch...

There is increasing epidemiological evidence in humans which associates low birthweight with later metabolic disorders, including insulin resistance and glucose intolerance. There is evidence that nutritional and hormonal factors (e.g. maternal protein restriction, exposure to excess maternal glucocorticoids) markedly influence intra-uterine growth and development. A picture is also emerging of...

background: fetal color doppler is important for evaluation of hypoxia in intrauterine growth restriction (iugr) fetus. objective: in this study we compare fetal and maternal color doppler with blood gas analysis to detect fetal acidosis. materials and methods: in this cross-sectional study we evaluated 100 hospitalized patients with iugr for comparison of color doppler results with arterial bl...