We analyzed diurnal variations in precipitation, surface pressure, and atmospheric static energy over the United States from observations and NCAR regional climate model (RegCM) simulations. Consistent with previous studies, the mean (1963-1993) pattern of the diurnal cycle of summer U.S. precipitation is characterized by late afternoon maxima over the Southeast and the Rocky Mountains and midn...

α4-Laminins, such as laminins 411 and 421, are mesenchymal laminins expressed by vascular and lymphatic endothelial cells, leukocytes and other normal cell types. These laminins are recognized by α6β1 and α6β4 integrins and MCAM (CD146), and promote adhesion and migration of the cells. α4-Laminins are also expressed and secreted by some tumor cells and strongly promote tumor cell migration. Mor...

Associate Professor, * Department of Biochemistry, Sinhgad Dental College and Hospital, Pune 411 041, Maharashtra, India. email: [email protected] Professor, Department of Endocrinology and Biochemistry, KEM Hospital Pune 411 011, Maharashtra, India 3 Assistant Professor, Department of Biochemistry, Pravara Institute of Medical Sciences, Loni 413 736, Maharashtra, India. Original Article

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7.11.5.1 Thermal and Photochemical Reactions 405 7.11.5.2 Reactions with Electrophiles 406 7.11.5.2.1 N-Alkylation 406 7.11.5.2.2 C-Allcylation and arylation 408 7.11.5.2.3 Reaction with diazonium ions 409 7.11.5.2.4 Oxidation of ring atoms 409 7.11.5.2.5 Halogenation 410 7.11.5.2.6 Metal complexes 410 7.11.5.3 Reactions with Nucleophiles 411 7.11.5.3.1 Reduction 411 7.11.5.3.2 Amination and hy...

Background: Transepidermal water loss (TEWL) has historically been used as an objective measure of skin barrier function and integrity. Variation in TEWL associated with variables such age anatomic location, yet regulatory agencies provide minimal guidance on controlling for variation settings vitro permeation testing (IVPT). Suggestions by the FDA broadly advise samples <15 g m-2h-1 IVPT studi...