This paper presents a compilation scheme, called ASP2AR, for translating ASP into event-driven action rules. For an ASP program, the generated program maintains a partial answer set as a pair of sets of tuples (called IN and OUT ) and propagates updates to these sets using action rules. To facilitate propagation, we encode each set as a finite-domain variable and treat additions of tuples into ...

Three commercially available pharmacophore generation programs, Catalyst/HipHop, DISCO and GASP, were compared on their ability to generate known pharmacophores deduced from protein-ligand complexes extracted from the Protein Data Bank. Five different protein families were included Thrombin, Cyclin Dependent Kinase 2, Dihydrofolate Reductase, HIV Reverse Transcriptase and Thermolysin. Target ph...

Autoresuscitation is a critical survival-promoting mechanism in mammals that allows recovery from primary apnea via hypoxia-induced gasping. Here we show, using head-out plethysmography, that gasping behavior is altered during autoresuscitation, and the autoresuscitation response is delayed, in neonatal 5-hydroxytryptamine (5-HT) neuron-deficient Pet-1 homozygous (Pet-1(-/-)) mice. When exposed...

The human cytomegalovirus (hCMV) encodes the G protein-coupled receptor (vGPCR) US28. This receptor signals constitutively and interacts with a broad range of chemokines, which are crucial to the pathophysiological significance and immunoregulatory aspects of this receptor. Chemokines and their receptors have been shown to be key determinants of tumor growth and formation of metastases. US28 ex...

This paper presents a method for designing a special type of asynchronous circuits, called Gasp circuits, and illustrates the method by a novel design of a low-latency, high-throughput FIFO, called a Square FIFO. The design method includes a graphical notation that permits the specification not only of circuit topology but also of the time separation between any two succeeding events. A Square ...

The Galway Astronomical Stokes Polarimeter (GASP) is an ultra-high-speed, full Stokes, astronomical imaging polarimeter based upon a Division of Amplitude Polarimeter. It has been developed to resolve extremely rapid stochastic (∼ms) variations in objects such as optical pulsars, RRATs and magnetic cataclysmic variables. GASP has no moving parts or modulated components, so the complete Stokes v...

The G a s p family of asynchronous circuits provides controls f o r simple pipelines, fo r branching and joining pipelines, f o r round-robin scatter and gathel; f o r datadependent scatter and gathel; and for join on demand through arbitration. The family is designed so that each stage operates at the speed of a three-inverter ring oscillator: Test chips in 0.35 micron technology exhibit throu...