نتایج جستجو برای: 17.57 and 20.62

تعداد نتایج: 17375341  

2015
Mirko Manetti, Marco Matucci - Cerinic,

SSc is a heterogeneous autoimmune CTD characterized by widespread vasculopathy, formation of autoantibodies and varying degrees of skin and major organ fibrosis [1, 2]. The life-threatening nature of this disease is well depicted by a 5-year mortality of 30 50% in a subset of patients with dcSSc and internal organ involvement. Despite the substantial research over the past decade, the aetiology...

2014
Claudia Korn, Beate Scholz, Junhao Hu, Kshitij Srivastava, Jessica Wojtarowicz, Tabea Arnsperger, Ralf H. Adams, Michael Boutros, Hellmut G. Augustin, Iris Augustin,

Multiple cell types involved in the regulation of angiogenesis express Wnt ligands. Although β-catenin dependent and independent Wnt signaling pathways have been shown to control angiogenesis, the contribution of individual cell types to activate these downstream pathways in endothelial cells (ECs) during blood vessel formation is still elusive. To investigate the role of ECs in contributing Wn...

Journal: :Nature 2012
JohnGilbey,

Journal: :Transactions of the Architectural Institute of Japan Summaries of Technical Papers 1966
HiroyukiMatsunaga,

2011
Jeffrey Phillips,

There are many ways an organization can approach innovation. On one end of the spectrum an organization can choose to have everyone submit any idea. On the other, innovation can be generated from a small, dedicated group of specialists. In the middle there are many variations along the way. This paper discusses the open innovation typology and the options for an organization making the decision...

2012
Bikram Basak, Pinaki Bhattacharya, Apurba Dey,

An extensive investigation was carried out to describe the kinetics of cell growth, substrate consumption, and product formation in the batch fermentation using starch as substrate. Evaluation of intrinsic kinetic parameters was carried out using a best-fit unstructured model. A nonlinear regression technique was applied for computational purpose. The Andrew’s model showed a comparatively bette...

Journal: :Nouvelles de l'estampe 2015
VéroniqueMeyer,

Journal: :Transactions of the Architectural Institute of Japan Summaries of Technical Papers 1965
TakashiKojima,

2016
Anu Saini,

The period of British rule from 1757 to 1900 is marked by major sociopolitical changes and scientific breakthroughs that impacted medical systems, institutions, and practitioners in India. In addition, historians have debated whether the colonial regime used Western medicine as a tool to expand and legitimize its rule. This paper reviews the secondary literature on this subject with emphasis on...

Journal: :World Allergy Organization Journal 2013
KirnSandhu, KarenAdams, ThanSoe, JaniceMccreadie, VijayChakravarti,

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