Background Mesenchyme stem cells (MSCs) are one of the widely used sources in tissue engineering and efficacy of cultural environment. In this survey, rat stem cells are used as coculture. Owing to main obstacle of embryo culture in the lab medium, the survival of embryo in lab is low in comparison with that of normal conditions. The purpose of this research is the survey of fertilization and c...

Background and Aims: Mesenchymal stem cells (MSCs) are a preferred cell source for the generation of hepatocyte-like cells in regenerative medicine. They can be isolated from different sources, including adipose tissues. The Raman spectroscopy approach was evaluated for quick and efficient identification of MSCs differentiation status and a broader perspective on cell differentiation. Material...

introduction: chemokine receptors are found on the surface of stem cells. there have been 19 distinct chemokine receptors described in mammals. chemokines are major players in migration and homing. therefore, changes in their levels or function can help us to increase the migratory potential of these cells. valproic acid differs in structure from other drugs in common use. the way in which valp...

Objective(s): Three-dimensional biomimetic scaffolds have widespread applications in biomedical tissue engineering due to similarity of their nanofibrous architecture to native extracellular matrix. Co-culture system has stimulatory effect on chondrogenesis of adult mesenchymal stem cells. This work presents a co-culture strategy using human articular chondrons and adipose-derived stem cells (A...

The use of stem cells is a breakthrough in medical biotechnology which brings regenerative therapy into new era. Over the past several decades, had been widely used as and Mesenchymal Stem Cells (MSCs) emerged promising therapeutic option. Currently are effective agents againts diseases due to their tissue protective repair mechanisms. This effect largely biomolecular properties including secre...

objective(s): adipose derived stem cells (adscs) can be engineered to express bone specific markers. the aim of this study is to evaluate repairing tibia in animal model with differentiated osteoblasts from autologous adscs in alginate scaffold. materials and methods: in this study, 6 canine’s adscs were encapsulated in alginate and differentiated into osteoblasts. alkaline phosphatase assay (a...

Subcutaneous adipose tissue has recently been attracting attention as a new cell source for regenerative medicine, replacing bone marrow. Among fibroblast-like cells, termed adipose stromal cells, stromalvascular cells, and preadipocytes, cells with potency to differentiate into not only adipocytes and blood vessels but also various lineages are present [1], and they are termed adipose-derived ...