Alien has been described as a corepressor for the thyroid hormone receptor (TR). Corepressors are coregulators that mediate gene silencing of DNA-bound transcriptional repressors. We describe here that Alien gene expression in vivo is regulated by thyroid hormone both in the rat brain and in cultured cells. In situ hybridization revealed that Alien is widely expressed in the mouse embryo and al...

In contrast o SF literature, most SF films have responded negatively to technolog, seeing it as a force in contemporary society that has had a deleterious effect on the quality of human life. Herbert Marcuse and Jacques Ellul, two of the most pessimistic analysts, have expressed their criticisms of technology in ways that also find expression in some of these films, which are preoccupied with m...

Many alien plants use animal vectors for dispersal of their diaspores (zoochory). If alien plants interact with native disperser animals, this can interfere with animal-mediated dispersal of native diaspores. Interference by alien species is known for frugivorous animals dispersing fruits of terrestrial plants by ingestion, transport and egestion (endozoochory). However, less attention has been...

We have found a novel gene (alien) that is expressed exclusively in the muscle attachment sites (apodemes) during embryogenesis in Drosophila. Antibodies raised against the Alien protein enable us to follow the developing attachments from state 11/12 until stage 16/17. The coding region of the Drosophila alien gene is highly conserved to a gene of unknown function, isolated from a plant (Loo et...

Alien plants have greatly altered some native plant communities and threaten others in Hawai`i Volcanoes National Park. The Park contains approximately 405 alien and 375 native vascular plant species. Desultory efforts were made to control alien plants until the 1980s, at which time a systematic program was initiated. The following strategies or actions have been taken to protect native species...

Increased livestock densities near artificial watering sites create disturbance gradients called piospheres. We studied responses of alien and native annual plants and native perennial plants within 9 piospheres in the Mojave Desert of North America. Absolute and proportional cover of alien annual plants increased with proximity to watering sites, whereas cover and species richness of native an...

The alien hand syndrome is a deeply puzzling phenomenon in which brain-damaged patients experience their limb performing seemingly purposeful acts without their intention. Furthermore, the limb may interfere with the actions of their normal limb. We report a case of alien hand syndrome following a left medial frontal and corpus callosum ischemic lesion. From our clinical observations and the pa...

Some members of nuclear hormone receptors, such as the thyroid hormone receptor (TR), silence gene expression in the absence of the hormone. Corepressors, which bind to the receptor's silencing domain, are involved in this repression. Hormone binding leads to dissociation of corepressors and binding of coactivators, which in turn mediate gene activation. Here, we describe the characteristics of...

Alien species are a major component of human-induced environmental change. Variation in the numbers of alien species found in different areas is likely to depend on a combination of anthropogenic and environmental factors, with anthropogenic factors affecting the number of species introduced to new locations, and when, and environmental factors influencing how many species are able to persist t...

Alien invasive species have been a seriously environment issue in the whole world. The ecological damages and economic influences of alien invasive species are analyzed in this article, and the government is suggested to strengthen the quarantine services, strictly manage the intentional introduction of alien species, and implement the risk supervision system for the introduction of alien species.