In various studies, Hofmann-type clathrates, given by the general formula ML2Ni(CN)4·G, were produced. Here M is a transition metal atom, L a ligand molecule or half of a bidentate ligand molecule, and G a guest molecule [1]. The clathrates are of interest because of their inclusion behavior and use as catalysts, anti-oxidants and stabilizing agents [2]. Infrared spectroscopy is one of the best...

Sudden cardiac death (SCD) refers to death after an unexpected sudden cardiac arrest in a patient with or without known structural heart disease. The incidence of SCD in the United States ranges from 300 000 to 460 000 events per year, depending on the criteria for SCD used for surveillance. SCD results from a complex interaction between preexisting cardiac substrates, either structural or gene...

The free radical theory of aging postulates that the production of intracellular reactive oxygen species is the major determinant of life span. Numerous cell culture, invertebrate, and mammalian models exist that lend support to this half-century-old hypothesis. Here we review the evidence that both supports and conflicts with the free radical theory and examine the growing link between mitocho...