Objective(s) The aim of the present study was to compare the therapeutic indices of several agents used in treatment of inflammatory conditions which included: Vitamin E, hydro-alcoholic extracts of Glycyrrhiza glabra, Matricaria aurea, dexamethasone, piroxicam and diclofenac using Wehi-164 fibrosarcoma cells. Materials and Methods Cytotoxicity evaluation was based on vital dye exclusion ass...

Bendazac or 1-benzyl-indazole 3-oxyacetic acid is a topical antinflammatory drug which in previous experiments was shown to preferentially inhibit inflammatory processes progressing towards necrosis (1). This activity has been temptatively related to a pre vention of protein denaturation (2-4). The aim of these experiments was to study effects of bendazac and hydrocortisone on heat-induced burn...

Herbal Medicines are a fast emerging trend in recent times, as they provide safer, effcective and economical treatment to patients. Azadirachta indica (neem) has been an integral part of health and oral care since times immemorial. It has shown to be an effective antimicrobial, antinflammatory and anticancer agent. In india it has been an indespensible part of oral care and is still a popular d...

D. Gatti1, S. Adami2, B. Canesi2, MA. Cimmino2, O. Della Casa2, M. Del Tacca2, C. Klersy3, G. Leardini2, P. Patrignani4, L. Punzi2, S. Bombardieri2 Cattedra di Reumatologia, Università di Verona; Centro Studi SIR; Dipartimento di Biometria ed Epidemiologia Clinica, IRCCS Policlinico San Matteo, Pavia; Cattedra di Farmacologia, Dipartimento di Medicina e Scienze dell’Invecchiamento, Università “...

BACKGROUND Salvinorin A (SA), the main active component of Salvia Divinorum, is a non-nitrogenous kappa opioid receptor (KOR) agonist. It has been shown to reduce acute pain and to exert potent antinflammatory effects. This study assesses the effects and the mode of action of SA on formalin-induced persistent pain in mice. Specifically, the SA effects on long-term behavioural dysfuctions and ch...

Amniotic membrane transplantation (AMT) leads to reduction of inflammatory symptoms and causes faster epithelisation in corneal ulcers and persistant epithelial defect. 21 patients with corneal ulcer (n = 18) or non-healing epithelial defect (n = 3) unresponsive to conventional treatment were included in the study. All patients were treated by AMT. Corneal epithelial cells in patients suffering...

Melatonin is a hormone that acts facilitating the appearance of physiological sleep It has also very evident antinflammatory and antioxidant capacities result in beneficial actions on aging processes cardiovascular system lungs where our group detected protective action against oxidative stress , inflammation apoptosis . Although melatonin not viricidal by itself some models viral infections it...