OBJECTIVE To prepare and evaluate the liver-targeted drug delivery system of Bufalin with higher liver uptake and stronger antitumor activity against hepatocellular carcinoma. METHODS Bufalin-loaded bovine serum albumin nanoparticle was prepared by desolvation method, to investigate the in vitro release performance and to evaluate the pharmacokinetic and tissue distribution. The antitumor act...

A ~ t T h e interaction of concanavalin A with a comprehensive series of carbohydrate-bovine serum albumin conjugates was investigated by agar gel diffusion and quantitative precipitation techniques. These studies showed that when conjugated to bovine serum albumin, those sugars which inhibited concanavalin A-polysaccharide interaction formed a precipitate with concanavalin A. The unexpected re...

Packed human red blood cells, diluted 1:1 with phosphate-buffered saline (PBS) containing 0-21% bovine serum albumin was used as a blood meal source for Anopheles farauti. Egg and larval production linearly increased with bovine serum albumin concentration in PBS. When the saline contained 9-21% bovine serum albumin, egg production was equivalent to that obtained when mosquitoes were fed direct...

BACKGROUND: Infectious Bovine Rhinotrachitis (IBR) caus-ed by Bovine Herpes Virus-1 (BoHV-1) was first, observed in one of the Tehran Industrial cattle breeders, with importation of cattle in 1965. Later, the isolation of bovine herpes virus approved the existence of the disease in the most of the provinces of the Iran. OBJECTIVES: Presence of antibodies against BoHV-1 was evaluated in young bo...

this study was aimed at the evaluation of the influence of storage under various conditions on the relative concentrations of major protein fractions and their proportion in bovine serum. blood samples were taken from six dairy cattle of a low-land black spotted breed and its crossbreeds. the separated blood serum was fractioned into aliquots. one aliquot was analysed immediately after the sepa...

Background and aims: Toxoplasma gondii is an obligate intracellular parasite which has the potential toinfect all warm-blooded animals. Sheep and cattle play a main role in the economy and their infectionto T. gondii, besides economic losses, can cause the infection of humans through the consumptionof raw meat and other products. In this study, we aimed to survey the prevalenc...

The results of examination of 375 bovine serum and 150 bovine milk samples for detection of bovine leukemia virus infection by the immunodiffusion technique were compared with those of an enzyme-linked immunosorbent assay (ELISA). It was concluded that the ELISA is another useful method for the detection of antibodies to bovine leukemia virus in serum and milk. The ELISA provides a quantitative...

In this data article, the fluorescence, UV-vis absorption and FTIR spectra data of BSA-AR1/AG50 system were presented, which were used for obtaining the binding characterization (such as binding constant, binding distance, binding site, thermodynamics, and structural stability of protein) between BSA and AR1/AG50.