The contents of cigarette smoke (gaseous and solid phases) have been attributed to a variety of diseases in the respiratory and cardiovascular systems and have been associated with development of different types of cancers. In respiratory system, these compounds specially cause epithelial cell injury, and interfere with mucocilliary transport (MTC). Various parts of Althea officinalis (family M...

BACKGROUND While the presence of the chitinase-like molecule YKL40 has been reported in COPD and asthma, its relevance to inflammatory processes elicited by cigarette smoke and common environmental allergens, such as house dust mite (HDM), is not well understood. The objective of the current study was to assess expression and function of BRP-39, the murine equivalent of YKL40 in a murine model ...

Background Exposure to cigarette smoke has numerous health risks for infants and children. Home smoking ban is a simple way to reduce the detrimental impacts of cigarette smoke. This study aimed to determine the prevalence of cigarette smoking bans in homes as well as associated factors in families with infants in Tehran, Iran. Materials and Methods This study was a population-based cross-secti...

Chronic bronchitis, a disease mainly of cigarette smokers, shares many clinical features with cystic fibrosis, a disease of altered ion transport, suggesting that the negative effects of cigarette smoke on mucociliary clearance may be mediated through alterations in ion transport. We tested the hypothesis that cigarette smoke extract would inhibit chloride secretion in human bronchial epithelia...

Cigarette smoking is associated with human cancers. It has been reported that most of the lung cancer deaths are caused by cigarette smoking (5,6,7,12). Although tobacco tars and related products in the particle phase of cigarette smoke are major causes of carcinogenic and mutagenic related diseases, cigarette smoke contains significant amounts of free radicals that are also considered as an i...

C igarette smoking is a major risk factor in the development of pulmonary emphysema, a chronic disorder thought to be caused by excess protease activity in lung. Although inhalation of cigarette smoke is associated with accumulation of polymorphonuclear leukocytes (PMN; a major source of preformed proteases) in the lung, cigarette smoke, by itself, is not chemotactic for PMN. Since alveolar mac...

BACKGROUND Cigarette smoking induces peripheral inflammatory responses in all smokers and is the major risk factor for neutrophilic lung disease such as chronic obstructive pulmonary disease. The aim of this study was to investigate the effect of cigarette smoke on neutrophil migration and on β2-integrin activation and function in neutrophilic transmigration through endothelium. METHODS AND R...

introduction: noise, as the most common pollutant in the industrial environment, can lead to hearing loss and negatively affect other organs such as the cardiovascular system. cigarette smoking is a popular habit among some workers, and can also have a negative effect on the cardiovascular system. this study aimed to investigate the effect of simultaneous exposure to noise and cigarette smoke o...

Owing to the increase in price of cigarettes in Korea, herbal cigarettes have received increasing attention as a non-smoking aid; however, its safety has hardly been studied. We analyzed some of the toxic components in the mainstream smoke of herbal cigarettes, performed a mutagenicity test on smoke condensates for safety assessment, and compared the results with the corresponding values of a g...