These are the type of controlled drug delivery systems, which release the drug in continuous manner by both dissolution controlled as well as diffusion controlled mechanisms. To control the release of the drugs, which are having different solubility properties, the drug is dispersed in swellable hydrophilic substances, an insoluble matrix of rigid non swellable hydrophobic materials or plastic ...

This review presents a comprehensive summary of the current understanding US-sensitive drug delivery systems for controlled release and activation. The typical mechanisms main factors affecting ultrasonic responsiveness carriers are summarized. Representative examples US-controlled activation highlighted. Finally, an outlook on this promising therapeutic strategy is provided.

In the past few years, nanomaterial-based drug delivery systems have been applied to enhance the efficacy of therapeutics and to alleviate negative effects through the controlled delivery of targeting and releasing agents. However, few drug carriers can achieve high targeting efficacy, even when targeting modalities and surface markers are introduced. Immunological problems have also limited th...

In the modern era of treatment many new approaches have been evolved for more efficient administration of drugs. One of such approach is the administration of drugs at times at which they are most effective and best tolerated. Chronotherapy is the approach where the availability of drug is timed to match rhythms of disease or disorders in order to optimize therapeutic responses and minimize sid...

Novel drug delivery systems for controlled-release of opioid agonists as a long time painkillers or opioid antagonists for opium, heroin, and alcohol addiction are under development or in clinical use today. In this article, the field of "new drug delivery systems" is momentarily reviewed from the viewpoint of the marketed opioid agonists/antagonists dosage forms today.

Oral delivery of drugs is by far the most preferable route of drug delivery . Oral-rate controlled drug delivery systems have an important area among novel drug delivery system. But these oral sustained release drug delivery systems suffer greatly due to their short gastric residence time/ gastric emptying time. Whereas prolonged gastric residence increases duration of drug release, reduces dru...

Nanotechnology by manipulation of characteristics of materials such as polymers and fabrication of nanostructures is able to provide superior drug delivery systems for better management and treatment of diseases. The nanostructures employed as drug delivery systems have multiple advantages which make them superior to conventional delivery systems. Nanotechnology is one approach to overcome chal...

nanotechnology has changed our lives dramatically and influenced every sector of the research, engineering and also business community. nanotechnology is a rapidly growing science of producing and utilizing nano-sized particles, that measure in nanometer. in other words, nanotechnology is the art of characterizing, manipulating and organizing matter systemically, at the nanometer scale, which h...

acrylic-type polymeric systems having degradable ester bonds linked to ibuprofen were synthesized and evaluated as materials for drug delivery. ibuprofen, as a non-steroidal anti-inflammatory drug, was linked to 2-hydroxyethyl methacrylate by activated ester methodology in one-pot procedure. the resulting methacrylic derivative of ibuprofen was copolymerized with 2-hydroxyethyl methacrylate and...

Oral drug delivery route is the most preferable route of drug delivery. It is due to various advantages of this route like ease of administration, patient compliance and flexibility in the formulations. Oral dosage form has really progressed from immediate release to site-specific delivery. The recent scientific and patented literature concluded that an increased interest in novel dosage forms ...