Cationic polymeric nanoparticles have great potential for developing drug delivery systemswith limited side effects for tumor medication. The goal of this research is investigation ofcationic dextran-spermine polymer (DS) efficacy for improvement of hydrophilic drug deliveryto negatively charged cancerous cells. Capecitabine (as a hydrophilic antineoplastic drug) wasloaded into the magnetic dex...

Ocular drug delivery research acceleratedly advanced towards. Ocular drug delivery necessitates and helps drug delivery scientists to. Urgent need to develop ocular drug delivery systems which provide controlled. Pdflucentis-prescribing.pdf accessed on 18 October 2010. Delivery system, therefore, desires an integrated knowledge of the drug molecule and the restrictions offered by the ocular rou...

Drug delivery technology is emerging as an interdisciplinary science aimed at improving human health. The controlled delivery of pharmacologically active agents to the specific site of action at the therapeutically optimal rate and dose regimen has been a major goal in designing drug delivery systems. Over the past few decades, there has been considerable interest in developing biodegradable dr...

Microfluidics is undoubtedly an influential technology that is currently revolutionizing the chemical and biological studies by replicating laboratory bench-top technology on a miniature chip-scale device. In the area of drug delivery science, microfluidics offers advantages, such as precise dosage, ideal delivery, target-precise delivery, sustainable and controlled release, multiple dosing, an...

Colchicine is a secondary metabolite, originally extracted from plants of the genius colchicum it consists of the dried ripe seeds of Colchicum autumnale Linn., colchicine effectively functions as a mitotic poison or spindle inhibitor but the major disadvantage of the colchicine is toxicity and non target cell (normal cell)effect. That toxicity and targeted drug delivery can be controlled by ca...

The objective of writing this review on hydrodynamically balanced systems (HBS) was collection of the recent literature. The design of hydrodynamically balanced drug delivery system is base on prolong GI residence time of drug in an area of the GI tract to maximize drug reaching its absorption. Gastrointestinal transit time of orally administered dosage forms are controlled by using gastro rete...

Gastric emptying is a complex process and makes in vivo performance of the drug delivery systems uncertain. In order to avoid this variability, efforts have been made to increase the retention time of the drug-delivery systems for more than 12 hours. The floating or hydrodynamically controlled drug delivery systems are useful in such application. From the formulation and technological point of ...

Oral controlled drug delivery systems represent the most popular form of sustained drug delivery systems for the obvious advantages of oral route of drug administration. Such systems release the drug with constant or variable release rates. The oral controlled release systems shows a typical pattern of drug release in which the drug concentration is maintained in the therapeutic window for a pr...