Waardenburg syndrome (WS) is an inherited sensorineural deafness condition in humans caused by melanocyte deficiencies in the inner ear and forelock. Mutation of microphthalmia-associated transcription factor (MITF) is known to produce WS type IIA whereas mutations of either endothelin (EDN) or its receptor endothelin receptor B (EDNRB) produce WS type IV. However, a link between MITF haploinsu...

Abstract: The paper develops a multi-objective planning framework for distribution network expansion with electric vehicle charging stations. Charging loads are modeled in the first place, and then integrated into the optimal distribution network expansion planning. The formulation is extended from the single objective of the economic cost minimization into three objectives with the additional ...

Abstract: Due to the energy savings and environmental protection they provide, plug-in electric vehicles (PEVs) are increasing in number quickly. Rapid development of PEVs brings new opportunities and challenges to the electricity distribution network’s dispatching. A high number of uncoordinated charging PEVs has significant negative impacts on the secure and economic operation of a distributi...

Insulator strings with several material and profiles are very common in overhead transmission lines. However, the electric field and voltage distribution of insulator string is uneven which may easily lead to corona, insulators’ surface deterioration and even flashover. So the calculation of the electric field and voltage distribution along them is a very important factor in the operation time....

The goal of this research is to construct causal gene networks for genetical genomics experiments using expression Quantitative Trait Loci (eQTL) mapping and Structural Equation Modeling (SEM). Unlike Bayesian Networks, this approach is able to construct cyclic networks, while cyclic relationships are expected to be common in gene networks. Reconstruction of gene networks provides important kno...

EDN-LD is a set of conventions for representing linked data using Extensible Data Notation (EDN) and a library for conveniently working with those representations in the Clojure programming language. It provides a lightweight alternative to existing linked data tools for many common use cases, much in the spirit of JSON-LD. We present the motivation and design of EDN-LD, and demonstrate how it ...

This paper presents the application of modified form of Particle Swarm Optimization as an optimization technique to the reconfiguration of electric distribution systems. The intended reconfiguration is an optimization and decision-making process which considers the maximization of the number of loads supplied associated to the minimization of the number of closed switches. A novel selection reg...

This paper presents the design of an auxiliary power distribution network for an electric vehicle. Efficiency is a key element in the design for any electric vehicle and a 48Vdc distribution network will be used throughout the vehicle. The high efficiency Cuk converter has been selected as the most appropriate topology to supply the various distributed loads. To achieve the best compromise betw...