Objective: To identify rapidly changing antibiotic susceptibility of ESBL & Uropathogens. Study Design: Comparative Cross-sectional prospective study. Setting: Allied Hospitals Peshawar Medical College. Period: 8th November 2021 to 5th March 2022. Material Methods: 10-15ml midstream urine was collected in a sterile container from 158 patients Pus cells, red blood and bacteria were examined ...

Vaborbactam (formerly RPX7009) is a new beta-lactamase inhibitor based on a cyclic boronic acid pharmacophore. The spectrum of beta-lactamase inhibition by vaborbactam and the impact of bacterial efflux and permeability on its activity were determined using a panel of strains with beta-lactamases cloned from various classes and a panel of Klebsiella pneumoniae carbapenemase 3 (KPC-3)-producing ...