Un cas de fihreuse dysplasie evoluant dcpuis dix ans a ete observe a l'hopital farahnaz de l'universite Melli de Teheran. La particu-larite in terssante de cettc patiente est tout d'abord la clegenerscence kystiquc de foyer de l'os iliaque droit et la multitude des fractures des membres ayant consolide dans des positions v1cieusc spon tanement. Presence d'un foyer temporal gauchf! de .forme scl...

Introduction: Pulmonary involvement secondary to Systemic Sclerosis (SSc) is the major cause of morbidity and mortality in SSc patients. We designed this study to determine the correlation of important lung function parameters with lung High Resolution CT (HRCT) scan findings. Materials and Methods: Thirty–two consecutive diffuse SSc patients with pulmonary fibrosis were enrolled in this cross...

BACKGROUND Noninvasive hepatic fibrosis scores that predict the presence of advanced fibrosis have been developed and validated in adult patients with NAFLD. The aims of our study were to assess the utility of commonly used adult fibrosis scores in pediatric NAFLD and to develop a pediatric specific fibrosis score that can predict advanced fibrosis. METHODS Consecutive children with biopsy-pr...

In recent years, the microbiome has been recognized as a key regulator of immune responses. Evidence suggests that changes in the microbiome can lead to chronic disease and even exacerbation of the disease. Impairment of innate immunity resulting from microbial incompatibility may worsen host susceptibility to infection and exacerbate chronic lung diseases. Specific microbes play a key role in ...

Medial canal fibrosis usually occurs as sequelae of known conditions such trauma, infection, or surgery. Rarely, it without an identifiable cause, hence the term idiopathic medial fibrosis. Regardless etiology, reportedly most successful treatment is A 52-year-old lady presented to us with bilateral reduced hearing and left ear tinnitus. There was no significant history suggest possible cause s...

A method that maximises the yield of viable enterocytes has been developed for the isolation of enterocytes from human jejunal biopsy specimens. These enterocytes have been used to study the values of intracellular free calcium and the rises in adenosine 3'5'-cyclic monophosphate (cAMP) induced by secretagogues in normal and cystic fibrosis cells. Basal intracellular free calcium of cystic fibr...

Abstract One of the earliest signs dysregulation homeostatic process fibrosis, associated with pathology in chronic conditions such as rheumatoid arthritis, is overexpression collagen type III (COL-3). Critically, there still relatively little known regarding identity cell types expressing gene encoding COL-3 (Col3a1). Identifying and characterizing Col3a1-expressing cells during development fi...