OBJECTIVES Metabolically healthy obese (MHO) phenotype describes an obese state with a favorable metabolic profile. However, the prognosis of this subpopulation remains controversial. We aimed to examine whether MHO phenotype is associated with progression of atherosclerotic activity, reflected as the changes in coronary artery calcification (CAC) over time. If so, we sought to determine the ro...

Forming limit diagrams (FLDs) are calculated based on both the Marciniak and Kuczynski (M-K)  model and the analysis proposed by Jones and Gillis (J-G). J-G analysis consisted of plastic deformation approximation by three deformation phases. These phases consisted of homogeneous deformation up to the maximum load (Phase I), deformation localization under constant load (phase II) and local necki...

This paper presents a new method for combining Fisher’s Linear Discriminant (FLD) and Multi Layer Perceptron (MLP) for face detection. The input patterns are first clustered into 10 face and 10 non-face clusters using K-means algorithm. Then, the FLD coefficients are calculated to obtain the optimal projection of face and non-face images. For each 19×19 pixel window, only 19 FLD coefficients ar...

Abstract Multi-fidelity optimization, which complements an expensive high-fidelity function with cheaper low-fidelity functions, has been successfully applied in many fields of structural optimization. In the present work, exemplary cross-die deep-drawing optimization problem is investigated to compare different objective functions and assess performance a multi-fidelity efficient global techni...

The intrinsic property of proteins to form structural motifs such as alpha helices and beta sheets leads to a complex phase behavior in which proteins can assemble into various types of aggregates including crystals, liquidlike phases of unfolded or natively folded proteins, and amyloid fibrils. Here we use a coarse-grained protein model that enables us to perform Monte Carlo simulations for de...

We investigate the effect of the ordering temperature (T) and film thickness (h(f)) on the surface morphology of flow-coated block copolymer (BCP) films of asymmetric poly(styrene-block-methyl methacrylate). Morphology transitions observed on the ordered film surface by atomic force microscopy (AFM) are associated with a perpendicular to a parallel cylinder BCP microphase orientation transition...