Population projections at a small area level are sensitive to random departures in temporal trends of population change components. In order to have robust trends for the county level projections in Costa Rica, the team in charge of forecasting decided to determine county clusters based on the past trends. In this paper, we compare three descriptive techniques used to build space-time clusters ...

The pigmented rat is an increasingly important model in visual neuroscience research, yet the lamination of retinal projections in the dLGN has not been examined in sufficient detail. From previous studies it was known that most of the rat dLGN receives monocular input from the contralateral eye, with a small island receiving predominantly ipsilateral projections. Here we revisit the question u...

Axonal branches from a subset of neurons in cerebral cortical layer 6 innervate both cortical layer 4 and the thalamus. As such, these neurons are poised to modulate thalamocortical transmission at multiple forebrain sites. Here, we examined the functional organization of the layer 6 intracortical projections in auditory, somatosensory, and visual cortical areas using an optogenetic approach to...

Many studies have claimed that hemispheric projections are split precisely at the foveal midline and so hemispheric asymmetry affects word recognition right up to the point of fixation. To investigate this claim, four-letter words and nonwords were presented to the left or right of fixation, either close to fixation in foveal vision or farther from fixation in extrafoveal vision. Presentation a...

We consider necessary conditions for the one-body reduced density matrix (1RDM) to correspond to a triplet wave function of a two-electron system. The conditions concern the occupation numbers and are different for the high spin projections, Sz = ±1, and the Sz = 0 projection. Hence, they can be used to test if an approximate 1RDM functional yields the same energies for both projections. We emp...

April 1, 2004 version) Software contracts help programmers enforce program properties that the language’s type system cannot express. Unlike types, contracts are (usually) enforced at run-time. When a contract fails, the contract system signals an error. Beyond such errors, contracts should have no other observable (functional) effect on the program’s results. In most implementations, however, ...

Transcriptional regulatory networks that control the morphologic and functional diversity of mammalian neurons are still largely undefined. Here we dissect the roles of the highly homologous POU-domain transcription factors Brn3a and Brn3b in retinal ganglion cell (RGC) development and function using conditional Brn3a and Brn3b alleles that permit the visualization of individual wild-type or mu...

Binocular vision requires an exquisite matching of projections from each eye to form a cohesive representation of the visual world. Eye-specific inputs are anatomically segregated, but in register in the visual thalamus, and overlap within the binocular region of primary visual cortex. Here, we show that the transmembrane protein Ten_m3 regulates the alignment of ipsilateral and contralateral p...

We introduce DLR, an extension of the n-ary propositionally closed description logic DLR to deal with attribute-labelled tuples (generalising the positional notation), projections of relations, and global and local objectification of relations, able to express inclusion, functional, key, and external uniqueness dependencies. The logic is equipped with both TBox and ABox axioms. We show how a si...

We introduce DLR ,̀ an extension of the n-ary propositionally closed description logic DLR to deal with attribute-labelled tuples (generalising the positional notation), projections of relations, and global and local objectification of relations, able to express inclusion, functional, key, and external uniqueness dependencies. The logic is equipped with both TBox and ABox axioms. We show how a s...