recently a potent anti-inflammatory effect of hydroalcoholic extract of the aerial parts of the sterile stems of stachys inflata has been reported. this study examined whether hydroalcoholic extract isolated from aerial parts of non-flowering stems of stachys inflata (standardized to contain 4.5% caffeic acid derivatives) reduce myocardial infarct size arising from coronary artery occlusion (30...

tendons are frequently targets of injury in sports and work. whether nonsteroidal anti-inflammatory drugs (nsaids) have beneficial effects on tendon healing is still a matter of debate. this study was conducted to evaluate effects of flunixin meglumine (fm) on tendon healing after experimentally induced acute trauma. twenty eight adult male new zealand white rabbits were subjected to complete t...

background and aims: inflammation is one of the defense mechanisms of body and unpleasant sensation of pain is caused by tissue damage. mostly, inflammation occurs through the release of inflammatory mediators. salvia officinalis is one of the most valuable medicinal kind of mint order. salvigenin is one of the active flavonoids existing in this plant. the aim of this study was to evaluate the ...

the month of ramadan, as a model of intermittent fasting, is a valuable opportunity to investigate the effects of dietary modifications on human metabolism. fasting improves insulin sensitivity, reduces atherogenic risk, oxidative stress, and inflammation. inflammation plays a key role in the pathogenesis of different disorders including atherosclerosis, metabolic syndrome and cardiovascular di...

conclusions rats fed with a 30% calorie-restricted diet in comparison with to ad libitum fed controls for 8 days had significantly more prominent regression of inflammation. results decline of both body weight and paw volume was significantly more prominent in the case than in the control rats within the study period (p < 0.001 and < 0.001, respectively). paw volume decrease was more prominent ...

background: deltamethrin (dm) is a synthetic pyrethroid insecticide which can lead to pathological effects in mammals through oxidative stress. on the other hand, virgin olive oil (voo) is a rich source of phenolic compounds with antioxidants. the aim of the present study was to determine the protective effects of voo against dm-induced hepatotoxicity. methods: thirty-six mice were randomly sep...

objective: the purpose of this study was to investigate the histological response to delib-erate perforation repaired using amalgam or mta either immediately or with delay on cats’ molars. materials and methods: twenty-eight molar teeth from four cats were used in this ex-perimental randomized study. after preparing the access cavity, the floor of pulp cham-bers were deliberately perforated wit...

multiple sclerosis (ms) is characterized by multiple areas of inflammation, demyelination and neurodegeneration. infiltrating th1 cd4+ t cells secrete proinflammatory cytokines. they stimulate the release of some cytokines, expression of adhesion molecules and these cytokines may cause damage to the myelin sheath and axons. in this study, we analyzed plasma levels and gene expressions of five i...

allergic airway inflammation is characterized by elaboration of cytokines and chemokines leading to recruitment of inflammatory leukocytes, predominantly eosinophils, to the airways. granulocyte macrophage colony stimulating factor (gm-csf) is generated in the lungs of human subjects with asthma in response to allergen challenge and is necessary for the development of allergen-induced bronchial...

background: the present study was designed to evaluate the secondary microglial activation processes after spinal cord injury (sci). methods: a quantitative histological study was performed to determine ed-1 positive cells, glial cell density, and cavitation size in untreated sci rats at days 1, 2, and 4, and weeks 1, 2, 3, and 4. results: the results of glial cell quantification along the 4900...