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نتایج جستجو برای Inflammatory cytokines

تعداد نتایج: 199999  
ژورنال: کومش 2020

Inflammatory cytokines increase in patients with type 2 diabetes (T2D) and metabolic syndrome. This review focuses on inflammatory cytokines such as C-reactive protein (CRP), tumor necrosis factor (TNF-α), and adiponectin, a cytokine produced by adipose tissue and associated with insulin sensitivity. Despite the major role of cytokines in the development of T2D, in the case of adiponectin still...

2008
M. Wilschanski,

• Vol 10 • November 2008 816 Inflammatory bowel disease in childhood is often diagnosed at a vulnerable time of growth and development. Malnutrition secondary to reduced appetite, increased metabolism and decreased absorptive capacity increase the risk of complications in children and adolescents diagnosed with IBD. Current treatment options include 5-aminosalicylic acid, antibiotics, corticost...

2001
David Delano, Nahel Awadallah, Bruce N. Cronstein, Nguyen D. Khoa, M. Carmen Montesinos, Allison B. Reiss,

Journal: :Chest 2000
S M Opal, V A DePalo,

The anti-inflammatory cytokines are a series of immunoregulatory molecules that control the proinflammatory cytokine response. Cytokines act in concert with specific cytokine inhibitors and soluble cytokine receptors to regulate the human immune response. Their physiologic role in inflammation and pathologic role in systemic inflammatory states are increasingly recognized. Major anti-inflammato...

2003
JOSE ALVARO-GRACIA,

Current models of rheumatoid arthritis (RA)' implicate lymphokines in the recruitment and activation of T cells in the synovium (1, 2) . However, adequate documentation of significant amounts of these proteins in the joint is limited . In fact, recent studies have found only very low levels of IFN-y in synovial fluid (SF) and tissue of patients with RA (3) . This relative lack of IFN-y seems co...

Journal: :Journal of the National Cancer Institute. Monographs 2001
D A Williams,

The cause of mucosal injury in inflammatory bowel disease (IBD) is not clear but likely involves infectious agents or other toxins followed by an abnormal immune response in genetically susceptible individuals. The inflammatory cytokines appear to play a key role in both the susceptibility of some individuals and the tissue damage that accompanies IBD. The generation of transgenic and gene-targ...

Journal: :Mediators of Inflammation 1997
P. L. Beck, J. L. Wallace,

Over the past decade, much has been learned regarding the role of various cytokines in the pathogenesis of inflammatory bowel disease. Several cytokine 'knockout' models in mice have been shown to develop colitis, while alterations in the production of various cytokines has been documented in human Crohn's disease and ulcerative colitis. In recent years, attempts have been made to treat these d...

2015
Javier Donate-Correa, Ernesto Martín-Núñez, Mercedes Muros-de-Fuentes, Carmen Mora-Fernández, Juan F. Navarro-González,

Probably, the most paradigmatic example of diabetic complication is diabetic nephropathy, which is the largest single cause of end-stage renal disease and a medical catastrophe of worldwide dimensions. Metabolic and hemodynamic alterations have been considered as the classical factors involved in the development of renal injury in patients with diabetes mellitus. However, the exact pathogenic m...

1989
Gary S. Firestein, Raymond Taetle, Kenneth Kaushansky,

A liquid culture technique was used to study 23 synovial fluids (SF) (21 from inflammatory joint diseases and 2 noninflammatory SF) and supernatants of two cultured rheumatoid arthritis (RA) synovial tissues for colony-stimulating factor (CSF). The proliferative responses of human peripheral blood macrophage-depleted non-T cells treated with synovial fluids, supernatants of synovial tissue expl...