نتایج جستجو برای: Linkage Design Factors
تعداد نتایج: 1996672 فیلتر نتایج به سال:
Vesicoureteral reflux (VUR) (OMIM %193000), a common cause of childhood renal failure, is strongly influenced by hereditary factors. Familial VUR most closely conforms to autosomal-dominant inheritance, but because of variable penetrance and expressivity, large multigenerational pedigrees tractable to linkage analysis have been difficult to ascertain. A single genome-wide study of familial VUR ...
BACKGROUND AND PURPOSE Genetic factors for brain arteriovenous malformation are unexplored because of the low incidence of familial cases, albeit local and familial clustering. We used a combination of a linkage study and an association study to explore the genetic background. METHODS A genome-wide linkage analysis was performed in 12 patients from 6 unrelated families using the GENEHUNTER pr...
Association mapping is a widely applied method for elucidating the genetic basis of phenotypic traits. However, factors such as linkage disequilibrium and levels of genetic diversity influence the power and resolution of this approach. Moreover, the presence of population subdivision among samples can result in spurious associations if not accounted for. As such, it is useful to have a detailed...
One in 5 people living with HIV are unaware of their status; they account for an estimated 51% of new infections. HIV transmission can be reduced through a "Test and Treat" strategy, which can decrease both viral load and risk behaviors. However, linkage of newly diagnosed HIV-positive persons to care has proved challenging. We report quantitative and qualitative data on linkage to care from HI...
For Genetic Analysis Workshop 15 Problem 2, we organized data from several ongoing studies designed to identify genetic and environmental risk factors for rheumatoid arthritis. Data were derived from the North American Rheumatoid Arthritis Consortium (NARAC), collaboration among Canadian researchers, the European Consortium on Rheumatoid Arthritis Families (ECRAF), and investigators from Manche...
Traceability ensures that software artifacts of subsequent phases of the development cycle are consistent. Few works have so far addressed the problem of automatically recovering traceability links between object-oriented (OO) design and code entities. Such a recovery process is required whenever there is no explicit support of traceability from the development process. The recovered informatio...
At present, multi-bar linkage mechanism is one of the most important directions of mechanical presses’ development. Utilizing the typical multi-linkage drawing mechanism of the plunger slide and compounding its parameters scientifically are a fairly effective way to realize the drawing technology demand. This paper established kinematics mode of the six-bar drawing mechanism by bar-group method...
This paper presents design modification to the existing standard wheelchair by incorporating an improved propulsion system and also braking and tilting systems that allow its full control with only one hand. The proposed design has the propulsion system with a chain drive powered through a four-bar linkage driven by the main handle. The desired direction of motion is obtained by moving the leve...
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